Prenatal opioid exposure: neurodevelopmental consequences and future research priorities

E Conradt, T Flannery, JL Aschner, RD Annett… - …, 2019 - publications.aap.org
Neonatal opioid withdrawal syndrome (NOWS) has risen in prevalence from 1.2 per 1000
births in 2000 to 5.8 per 1000 births in 2012. Symptoms in neonates may include high …

Cognitive and behavioral impact on children exposed to opioids during pregnancy

JJ Larson, DL Graham, LT Singer, AM Beckwith… - …, 2019 - publications.aap.org
The developmental impact of opioid use during pregnancy is a subject of ongoing debate.
Short-term neonatal outcomes, such as lower birth weight and neonatal abstinence …

Cognitive outcomes of young children after prenatal exposure to medications for opioid use disorder: a systematic review and meta-analysis

LF Nelson, VK Yocum, KD Patel, F Qeadan… - JAMA network …, 2020 - jamanetwork.com
Importance The number of children with prenatal opioid exposure to medication for addiction
treatment (MAT) with methadone and buprenorphine for maternal opioid use disorder is …

Effects of competing narratives on public perceptions of opioid pain reliever addiction during pregnancy

A Kennedy-Hendricks, EE McGinty… - Journal of Health …, 2016 - read.dukeupress.edu
Opioid pain reliever addiction has increased among women of reproductive age over the
last fifteen years. News media and public attention have focused on the implications of this …

Nonpharmacological management of neonatal abstinence syndrome: a review of the literature

G Ryan, J Dooley, L Gerber Finn… - The journal of maternal …, 2019 - Taylor & Francis
Background: Infants with neonatal abstinence syndrome (NAS) experience withdrawal that
occurs as a result of termination of placental opioid supply following delivery. Common …

Neonatal abstinence syndrome

M Grossman, A Berkwitt - Seminars in perinatology, 2019 - Elsevier
Neonates exposed prenatally to opioids will often develop a collection of withdrawal signs
known as neonatal abstinence syndrome (NAS). The incidence of NAS has substantially …

Perinatal fentanyl exposure leads to long-lasting impairments in somatosensory circuit function and behavior

JB Alipio, C Haga, ME Fox, K Arakawa… - Journal of …, 2021 - Soc Neuroscience
One consequence of the opioid epidemic are lasting neurodevelopmental sequelae
afflicting adolescents exposed to opioids in the womb. A translationally relevant and …

Neonatal abstinence syndrome and early childhood morbidity and mortality in Washington state: a retrospective cohort study

CE Witt, KE Rudd, P Bhatraju, FP Rivara… - Journal of …, 2017 - nature.com
Objective: The objective of the study was to evaluate the association between neonatal
abstinence syndrome (NAS) and long-term childhood morbidity and infant mortality. Study …

Environmental enrichment mitigates the long-lasting sequelae of perinatal fentanyl exposure in mice

JB Alipio, LM Riggs, M Plank, A Keller - Journal of Neuroscience, 2022 - Soc Neuroscience
The opioid epidemic is a rapidly evolving societal issue driven, in part, by a surge in
synthetic opioid use. A rise in fentanyl use among pregnant women has led to a 40-fold …

Neonatal opioid withdrawal syndrome (NOWS): a transgenerational echo of the opioid crisis

AE Weller, RC Crist, BC Reiner… - Cold Spring …, 2021 - perspectivesinmedicine.cshlp.org
The incidence of neonatal opioid withdrawal syndrome (NOWS) has increased substantially
in the setting of the opioid epidemic, a major public health problem in the United States. At …