[HTML][HTML] Brain-derived neurotrophic factor in Alzheimer's disease and its pharmaceutical potential
L Gao, Y Zhang, K Sterling, W Song - Translational Neurodegeneration, 2022 - Springer
Synaptic abnormalities are a cardinal feature of Alzheimer's disease (AD) that are known to
arise as the disease progresses. A growing body of evidence suggests that pathological …
arise as the disease progresses. A growing body of evidence suggests that pathological …
[HTML][HTML] Neurotrophic factor BDNF, physiological functions and therapeutic potential in depression, neurodegeneration and brain cancer
Brain-derived neurotrophic factor (BDNF) is one of the most distributed and extensively
studied neurotrophins in the mammalian brain. BDNF signals through the tropomycin …
studied neurotrophins in the mammalian brain. BDNF signals through the tropomycin …
NTRK fusion-positive cancers and TRK inhibitor therapy
N TRK gene fusions involving either NTRK1, NTRK2 or NTRK3 (encoding the neurotrophin
receptors TRKA, TRKB and TRKC, respectively) are oncogenic drivers of various adult and …
receptors TRKA, TRKB and TRKC, respectively) are oncogenic drivers of various adult and …
[HTML][HTML] The role of BDNF on neural plasticity in depression
T Yang, Z Nie, H Shu, Y Kuang, X Chen… - Frontiers in cellular …, 2020 - frontiersin.org
Using behavioral, pharmacological, and molecular methods, lots of studies reveal that
depression is closely related to the abnormal neural plasticity processes occurring in the …
depression is closely related to the abnormal neural plasticity processes occurring in the …
[HTML][HTML] BDNF: a key factor with multipotent impact on brain signaling and synaptic plasticity
P Kowiański, G Lietzau, E Czuba, M Waśkow… - Cellular and molecular …, 2018 - Springer
Brain-derived neurotrophic factor (BDNF) is one of the most widely distributed and
extensively studied neurotrophins in the mammalian brain. Among its prominent functions …
extensively studied neurotrophins in the mammalian brain. Among its prominent functions …
Brain‐derived neurotrophic factor, depression, and physical activity: making the neuroplastic connection
C Phillips - Neural plasticity, 2017 - Wiley Online Library
Brain‐derived neurotrophic factor (BDNF) is a neurotrophin that is vital to the survival,
growth, and maintenance of neurons in key brain circuits involved in emotional and …
growth, and maintenance of neurons in key brain circuits involved in emotional and …
BDNF and hippocampal synaptic plasticity
G Leal, CR Bramham, CB Duarte - Vitamins and hormones, 2017 - Elsevier
Brain-derived neurotrophic factor (BDNF) belongs to a family of small secreted proteins that
also include nerve growth factor, neurotrophin 3, and neurotrophin 4. BDNF stands out …
also include nerve growth factor, neurotrophin 3, and neurotrophin 4. BDNF stands out …
[HTML][HTML] The involvement of BDNF, NGF and GDNF in aging and Alzheimer's disease
Aging is a normal physiological process accompanied by cognitive decline. This aging
process has been the primary risk factor for development of aging-related diseases such as …
process has been the primary risk factor for development of aging-related diseases such as …
Brain-derived neurotrophic factor in mood disorders and antidepressant treatments
Levels of brain-derived neurotrophic factor (BDNF) are reduced in the brain and serum of
depressed patients and at least the reduction in serum levels is reversible upon successful …
depressed patients and at least the reduction in serum levels is reversible upon successful …
[HTML][HTML] Targeting neurotrophins to specific populations of neurons: NGF, BDNF, and NT-3 and their relevance for treatment of spinal cord injury
KM Keefe, IS Sheikh, GM Smith - International journal of molecular …, 2017 - mdpi.com
Neurotrophins are a family of proteins that regulate neuronal survival, synaptic function, and
neurotransmitter release, and elicit the plasticity and growth of axons within the adult central …
neurotransmitter release, and elicit the plasticity and growth of axons within the adult central …