Ethnobotany and the role of plant natural products in antibiotic drug discovery
The crisis of antibiotic resistance necessitates creative and innovative approaches, from
chemical identification and analysis to the assessment of bioactivity. Plant natural products …
chemical identification and analysis to the assessment of bioactivity. Plant natural products …
Small molecules in the treatment of COVID-19
S Lei, X Chen, J Wu, X Duan, K Men - Signal transduction and targeted …, 2022 - nature.com
The outbreak of COVID-19 has become a global crisis, and brought severe disruptions to
societies and economies. Until now, effective therapeutics against COVID-19 are in high …
societies and economies. Until now, effective therapeutics against COVID-19 are in high …
Biologically active isoquinoline alkaloids covering 2014–2018
XF Shang, CJ Yang… - Medicinal research …, 2020 - Wiley Online Library
Isoquinoline alkaloids, an important class of N‐based heterocyclic compounds, have
attracted considerable attention from researchers worldwide since the early 19th century …
attracted considerable attention from researchers worldwide since the early 19th century …
Quinoline and its derivatives as corrosion inhibitors: a review
Quinoline is a nitrogenous bicyclic heterocyclic compound with molecular formula of C 9 H 7
N in which pyridine moiety is fused with benzene ring. Quinoline and its derivatives are …
N in which pyridine moiety is fused with benzene ring. Quinoline and its derivatives are …
Dual inhibitors of human DNA topoisomerase II and other cancer-related targets
Human DNA topoisomerase II is an important target in anticancer therapy. Despite the
clinical success of drugs that target topoisomerase II, the development of resistant cancer …
clinical success of drugs that target topoisomerase II, the development of resistant cancer …
Biosynthesis investigations of terpenoid, alkaloid, and flavonoid antimicrobial agents derived from medicinal plants
W Huang, Y Wang, W Tian, X Cui, P Tu, J Li, S Shi… - Antibiotics, 2022 - mdpi.com
The overuse of antibiotics in the past decades has led to the emergence of a large number
of drug-resistant microorganisms. In recent years, the infection rate caused by multidrug …
of drug-resistant microorganisms. In recent years, the infection rate caused by multidrug …
Bacterial terpenome
Covering: up to mid-2020 Terpenoids, also called isoprenoids, are the largest and most
structurally diverse family of natural products. Found in all domains of life, there are over 80 …
structurally diverse family of natural products. Found in all domains of life, there are over 80 …
Quinazoline-based VEGFR-2 inhibitors as potential anti-angiogenic agents: A contemporary perspective of SAR and molecular docking studies
M Moradi, A Mousavi, Z Emamgholipour… - European Journal of …, 2023 - Elsevier
Angiogenesis, the formation of new blood vessels from the existing vasculature, is pivotal in
the migration, growth, and differentiation of endothelial cells in normal physiological …
the migration, growth, and differentiation of endothelial cells in normal physiological …
Therapeutic progression of quinazolines as targeted chemotherapeutic agents
R Bansal, A Malhotra - European Journal of Medicinal Chemistry, 2021 - Elsevier
Presently cancer is a grave health issue with predominance beyond restrictions. It can affect
any organ of the body. Most of the available chemotherapeutic drugs are highly toxic, not …
any organ of the body. Most of the available chemotherapeutic drugs are highly toxic, not …
Synthetic and medicinal perspective of quinolines as antiviral agents
In current scenario, various heterocycles have come up exhibiting crucial role in various
medicinal agents which are valuable for mankind. Out of diverse range of heterocycle …
medicinal agents which are valuable for mankind. Out of diverse range of heterocycle …