Crohn's disease (CD) is a major form of inflammatory bowel disease characterized by
transmural inflammation along the alimentary tract. Changes in the microbial composition …

Background There is an increasing body of evidence showing that earlier use of biologics
improves clinical outcomes in Crohn's disease (CD). Aim To perform a systematic review …

Background & Aims Endoscopic and histologic remission have emerged as key therapeutic
goals in the management of inflammatory bowel diseases (IBD) that are associated with …

Introduction A dysregulated intestinal T cell response is presumed in patients with
inflammatory bowel disease [IBD]. In this longitudinal study, we investigated the changes in …

Abstract Background and Aims: Efforts to slow or prevent the progressive course of
inflammatory bowel diseases [IBD] include early and intensive monitoring and treatment of …

Background Recent trends indicate a change in the epidemiology of inflammatory bowel
diseases (IBD), with previously low incidence areas now reporting a progressive rise in the …

The burden of inflammatory bowel disease (IBD) in older adults (ie, aged over 60 years old)
is increasing due to a combination of an ageing population with compounding prevalence of …

Background and aims: We examined the impact of disease duration on clinical outcomes
and safety in a post hoc analysis of a remission maintenance trial with adalimumab in …

Background This study sought to re-estimate the cumulative incidence of perianal or
rectovaginal fistulas and the associated proctectomy rate in the prebiologic era vs the …

Abstract Background and Aims The incidence of inflammatory bowel disease (IBD) is
increasing in C hina with urbanization and socioeconomic development. There is however a …