Background The comparative accuracy of bowel ultrasound [US] versus magnetic
resonance enterography [MRE] in combination with colonoscopy [CS] in assessing Crohn's …

Crohn's disease (CD) is a chronic relapsing and remitting disease that can affect any
segments of the gastrointestinal tract. More than 50% of patients with CD develop stricturing …

Background Endoscopic balloon dilatation (EBD) is recognised treatment for symptomatic
Crohn's strictures. Several case series report its efficacy. A systematic analysis for overall …

Objective This phase II, randomised, double-blind, placebo-controlled clinical trial was
designed to evaluate the efficacy and safety of PF-00547659, a fully human monoclonal …

Crohn's disease is increasing in prevalence worldwide. It arises from a complex interplay
between both genetic predisposition and environmental influence. A search of databases …

The use of biologic agents including anti-tumor necrosis factor monoclonal antibodies
followed by anti-integrins and anti-interleukins has drastically changed the treatment …

Summary Background Patients with Crohn's disease (CD) have serologic responses to
various microbial antigens. Serologic markers are associated with aggressive forms of …

Crohn's disease (CD) is a chronic progressive destructive inflammatory bowel disease. As in
rheumatoid arthritis, there is increasing evidence that early treatment initiation with disease …

AIM: To evaluate the demographic characteristics and clinical phenotypes of inflammatory
bowel disease (IBD) in a geographic area in Northeastern Brazil. METHODS: This …

Background Intestinal fibrosis resulting in (sub) obstruction is a common complication of
Crohn's disease (CD). Rho kinases (ROCKs) play multiple roles in TGFβ-induced …