Real-time motion management in MRI-guided radiotherapy: Current status and AI-enabled prospects

E Lombardo, J Dhont, D Page, C Garibaldi… - Radiotherapy and …, 2023 - Elsevier
MRI-guided radiotherapy (MRIgRT) is a highly complex treatment modality, allowing
adaptation to anatomical changes occurring from one treatment day to the other (inter …

[HTML][HTML] A review of the clinical introduction of 4D particle therapy research concepts

B Knäusl, G Belotti, J Bertholet, J Daartz… - Physics and imaging in …, 2024 - Elsevier
Background and purpose Many 4D particle therapy research concepts have been recently
translated into clinics, however, remaining substantial differences depend on the indication …

Patient breathing motion and delivery specifics influencing the robustness of a proton pancreas irradiation

B Knäusl, F Lebbink, P Fossati, E Engwall, D Georg… - Cancers, 2023 - mdpi.com
Simple Summary The study retrospectively analysed the clinical proton treatment strategy for
pancreas patients with small moving tumours. Seventeen hypofractionated proton treatment …

[HTML][HTML] A survey of practice patterns for adaptive particle therapy for interfractional changes

P Trnkova, Y Zhang, T Toshito, B Heijmen… - Physics and imaging in …, 2023 - Elsevier
Background and purpose Anatomical changes may compromise the planned target
coverage and organs-at-risk dose in particle therapy. This study reports on the practice …

[HTML][HTML] ScatterNet for projection-based 4D cone-beam computed tomography intensity correction of lung cancer patients

H Schmitz, A Thummerer, M Kawula… - Physics and Imaging in …, 2023 - Elsevier
Background and purpose: In radiotherapy, dose calculations based on 4D cone beam CTs
(4DCBCTs) require image intensity corrections. This retrospective study compared the dose …

[HTML][HTML] Parameter based 4D dose calculations for proton therapy

F Lebbink, S Stocchiero, P Fossati, E Engwall… - Physics and Imaging in …, 2023 - Elsevier
Background and purpose Retrospective log file-based analysis provides the actual dose
delivered based on the patient's breathing and the daily beam-delivery dynamics. To predict …

Surveying the clinical practice of treatment adaptation and motion management in particle therapy

B Knäusl, VT Taasti, P Poulsen… - Physics and Imaging in …, 2023 - phiro.science
Due to the limited number of particle therapy centres worldwide, the outcome of these two
surveys is very powerful and proved a broad overview of actual clinical practice. Assessing …

[HTML][HTML] Automatic lung segmentation of magnetic resonance images: A new approach applied to healthy volunteers undergoing enhanced Deep-Inspiration-Breath …

JH Missimer, F Emert, AJ Lomax, DC Weber - Physics and imaging in …, 2024 - Elsevier
Background and purpose Respiratory suppression techniques represent an effective motion
mitigation strategy for 4D-irradiation of lung tumors with protons. A magnetic resonance …

[PDF][PDF] Patient breathing motion and delivery specifics influencing the robustness of a proton pancreas irradiation. Cancers 2023; 15: 2550

B Knäusl, F Lebbink, P Fossati, E Engwall, D Georg… - 2023 - academia.edu
Motion compensation strategies in particle therapy depend on the anatomy, motion
amplitude and underlying beam delivery technology. This retrospective study on pancreas …

[HTML][HTML] Explicitly encoding the cyclic nature of breathing signal allows for accurate breathing motion prediction in radiotherapy with minimal training data

A Renner, I Gulyas, M Buschmann, G Heilemann… - Physics and Imaging in …, 2024 - Elsevier
Background and purpose Active breathing motion management in radiotherapy consists of
motion monitoring, quantification and mitigation. It is impacted by associated latencies of a …