The imaging of specific molecular targets that are associated with cancer should allow
earlier diagnosis and better management of oncology patients. Positron emission …

Drug development is a risky business. Success or failure often depends on selecting one or
two molecules for development from many choices offered by the engines of high …

With the release of the landmark report Toxicity Testing in the 21st Century: A Vision and a
Strategy, the US National Academy of Sciences, in 2007, precipitated a major change in the …

Advances in molecular biology and toxicology are paving the way for major improvements in
the evaluation of the hazards posed by the large number of chemicals found at low levels in …

Positron emission tomography (PET) is a non-invasive imaging technology which provides a
unique window on the physiology and function of living organisms. It uses short-lived …

Positron emission tomography (PET) is well established as an important research and
clinical molecular imaging modality. Although the size differences between humans and …

Positron Emission Tomography is a high-resolution, sensitive, functional imaging technique,
which can efficiently give access to the distribution, pharmacokinetics and-dynamics of a …

Positron emission tomography (PET) is becoming more frequently used by medicinal
chemists to facilitate the selection of the most promising lead compounds for further …

▪ Abstract Biological research has been accelerated by the development of noninvasive
imaging techniques and by use of genetically engineered mice to model human diseases …

Better mechanistic understanding of disease through mapping of the human and mouse
genomes enables rethinking of human infirmity. In the case of cancer, eg, we may begin to …