[HTML][HTML] Role of the epithelial barrier in intestinal fibrosis associated with inflammatory bowel disease: relevance of the epithelial-to mesenchymal transition
DC Macias-Ceja, MT Mendoza-Ballesteros… - Frontiers in Cell and …, 2023 - frontiersin.org
In inflammatory bowel disease (IBD), chronic inflammation in the gastrointestinal tract can
lead to tissue damage and remodelling, which can ultimately result in fibrosis. Prolonged …
lead to tissue damage and remodelling, which can ultimately result in fibrosis. Prolonged …
[HTML][HTML] Intestinal Fibrogenesis in Inflammatory Bowel Diseases: Exploring the Potential Role of Gut Microbiota Metabolites as Modulators
S Cicchinelli, S Gemma, G Pignataro, A Piccioni… - Pharmaceuticals, 2024 - mdpi.com
Fibrosis, sustained by the transformation of intestinal epithelial cells into fibroblasts
(epithelial-to-mesenchymal transition, EMT), has been extensively studied in recent …
(epithelial-to-mesenchymal transition, EMT), has been extensively studied in recent …
Continuous genetic monitoring of transient mesenchymal gene activities in distal tubule and collecting duct epithelial cells during renal fibrosis
Z Xu, S Zhang, T Han, L Cai, S Zhong… - Journal of Cellular …, 2024 - Wiley Online Library
Epithelial cells (ECs) have been proposed to contribute to myofibroblasts or fibroblasts
through epithelial‐mesenchymal transition (EMT) during renal fibrosis. However, since EMT …
through epithelial‐mesenchymal transition (EMT) during renal fibrosis. However, since EMT …
[HTML][HTML] The IL-33-ST2 axis plays a vital role in endometriosis via promoting epithelial–mesenchymal transition by phosphorylating β-catenin
J Ruan, Q Tian, S Li, X Zhou, Q Sun, Y Wang… - Cell Communication and …, 2024 - Springer
Abstract Objectives Interleukin 33 (IL-33) is a crucial inflammatory factor that functions as an
alarm signal in endometriosis (EMs). Epithelial-mesenchymal transition (EMT), a process …
alarm signal in endometriosis (EMs). Epithelial-mesenchymal transition (EMT), a process …
[HTML][HTML] Up-regulation of long non-coding RNA H19 ameliorates renal tubulointerstitial fibrosis by reducing lipid deposition and inflammatory response through …
Y Jiang, F Ma, J Wang, X Chen, L Xue, X Chen… - Non-coding RNA …, 2024 - Elsevier
Long non-coding RNA (lncRNA) H19 is an extensively studied lncRNA that is related to
numerous pathological changes. Our previous findings have documented that serum …
numerous pathological changes. Our previous findings have documented that serum …
[HTML][HTML] Deciphering the molecular nexus of BTG2 in periodontitis and diabetic kidney disease
B Pan, Y Teng, R Wang, D Chen, H Chen - BMC Medical Genomics, 2024 - Springer
Objective To investigate the role of BTG2 in periodontitis and diabetic kidney disease (DKD)
and its potential underlying mechanism. Methods Gene expression data for periodontitis and …
and its potential underlying mechanism. Methods Gene expression data for periodontitis and …
[HTML][HTML] α-Mangostin reduces hypertension in spontaneously hypertensive rats and inhibits EMT and fibrosis in Ang II-induced HK-2 cells
Y Xu, J Wu, L Gao, H Lin, Z Yang, X Liu… - International Journal of …, 2024 - medsci.org
Hypertension affects a large number of individuals globally and is a common cause of
nephropathy, stroke, ischaemic heart disease and other vascular diseases. While many anti …
nephropathy, stroke, ischaemic heart disease and other vascular diseases. While many anti …
lncRNA 信号通路在慢性肾脏病治疗中的作用研究进展.
李佳倡， 冯佳楠， 魏佳莉 - Journal of Modern Medicine & …, 2024 - search.ebscohost.com
慢性肾脏病(CKD) 是指多种原因引起的慢性肾脏结构和功能障碍, 肾纤维化是其常见病理表现之
一, 主要包括肾功能从受损直至完全丧失的整个过程. 长链非编码RNA (lncRNA) …
一, 主要包括肾功能从受损直至完全丧失的整个过程. 长链非编码RNA (lncRNA) …
NR5A2 promotes epithelial-to-mesenchymal transition in renal fibrosis by targeting MMP25 transcription
G Chen, W Shan, Y Chen, W Wang, X Li - 2024 - researchsquare.com
Epithelial-to-mesenchymal transition (EMT) is crucial for the progression of renal
tubulointerstitial fibrosis, typically leading to end-stage renal failure. The role of Nuclear …
tubulointerstitial fibrosis, typically leading to end-stage renal failure. The role of Nuclear …