[HTML][HTML] Platelet-cancer interplay: molecular mechanisms and new therapeutic avenues

A Braun, HJ Anders, T Gudermann… - Frontiers in …, 2021 - frontiersin.org
Although platelets are critically involved in thrombosis and hemostasis, experimental and
clinical evidence indicate that platelets promote tumor progression and metastasis through a …

[HTML][HTML] Tumor educated platelet: the novel BioSource for cancer detection

S Ding, X Dong, X Song - Cancer Cell International, 2023 - Springer
Platelets, involved in the whole process of tumorigenesis and development, constantly
absorb and enrich tumor-specific substances in the circulation during their life span, thus …

Validation of a machine learning approach for venous thromboembolism risk prediction in oncology

P Ferroni, FM Zanzotto, N Scarpato… - Disease …, 2017 - Wiley Online Library
Using kernel machine learning (ML) and random optimization (RO) techniques, we recently
developed a set of venous thromboembolism (VTE) risk predictors, which could be useful to …

COMPASS-CAT versus Khorana risk assessment model for predicting venous thromboembolic events in patients with non-small cell lung cancer on active treatment …

H Abdel-Razeq, B Sharaf, MJ Al-Jaghbeer… - Journal of Thrombosis …, 2023 - Springer
Cancer patients are at higher risk for venous thromboembolism (VTE). Several risk
assessment models (RAM), including the Khorana and COMPASS-CAT, were developed to …

[HTML][HTML] Galectin functions in cancer-associated inflammation and thrombosis

L Kruk, A Braun, E Cosset, T Gudermann… - Frontiers in …, 2023 - frontiersin.org
Galectins are carbohydrate-binding proteins that regulate many cellular functions including
proliferation, adhesion, migration, and phagocytosis. Increasing experimental and clinical …

[HTML][HTML] Thromboembolic events in cancer patients on active treatment with cisplatin-based chemotherapy: another look!

H Abdel-Razeq, A Mansour, H Abdulelah… - Thrombosis journal, 2018 - Springer
Background The risk of thromboembolic events is higher among cancer patients, especially
in patients undergoing chemotherapy. Cisplatin-based regimens claim to be associated with …

Discovery of 5-Hydroxy-1, 4-naphthoquinone (Juglone) Derivatives as Dual Effective Agents Targeting Platelet-Cancer Interplay through Protein Disulfide Isomerase …

YP Juang, JY Tsai, WL Gu, HC Hsu… - Journal of Medicinal …, 2024 - ACS Publications
In this study, a series of 2-and/or 3-substituted juglone derivatives were designed and
synthesized. Among them, 9, 18, 22, 30, and 31 showed stronger inhibition activity against …

[HTML][HTML] The application of the lymphoma international prognostic index to predict venous thromboembolic events in diffuse large B-cell lymphoma patients

H Abdel-Razeq, M Ma'koseh, R Abdel-Razeq… - Frontiers in …, 2021 - frontiersin.org
Background Venous thromboembolic events (VTE) are commonly encountered in patients
with lymphoma. Several risk assessments models (RAM) had attempted to identify higher …

The Application of Existing Risk Assessment Models (RAMS) to Predict the Occurrence of Venous Thromboembolic Events among Patients with Classic Hodgkin …

M Ma'koseh, A Abufara, D Albaghdadi… - Journal of Clinical …, 2024 - mdpi.com
Background: A majority of patients included in risk assessment models (RAMs) developed to
predict venous thromboembolic events (VTE) in lymphoma were non-Hodgkin lymphoma …

Predictors of venous thromboembolism in patients with testicular germ cell tumors: a retrospective study

H Abdel-Razeq, F Tamimi… - Clinical and Applied …, 2021 - journals.sagepub.com
Malignancy, including testicular tumors, significantly increases the risk of venous
thromboembolism (VTE). In this study, we search for predictors that may help identify …