Evaluation of hemp (Cannabis sativa L.) as an industrial crop: a review

M Rehman, S Fahad, G Du, X Cheng, Y Yang… - … Science and Pollution …, 2021 - Springer
Rising human population has increased the utilization of available resources for food,
clothes, medicine, and living space, thus menacing natural environment and mounting the …

[HTML][HTML] Anandamide and other N-acylethanolamines: A class of signaling lipids with therapeutic opportunities

ED Mock, B Gagestein, M van der Stelt - Progress in Lipid Research, 2023 - Elsevier
Abstract N-acylethanolamines (NAEs), including N-palmitoylethanolamine (PEA), N-
oleoylethanolamine (OEA), N-arachidonoylethanolamine (AEA, anandamide), N …

[HTML][HTML] Review of the neurological benefits of phytocannabinoids

J Maroon, J Bost - Surgical neurology international, 2018 - ncbi.nlm.nih.gov
Background: Numerous physical, psychological, and emotional benefits have been
attributed to marijuana since its first reported use in 2,600 BC in a Chinese pharmacopoeia …

Recent development of multifunctional agents as potential drug candidates for the treatment of Alzheimer's disease

N Guzior, A Wieckowska, D Panek… - Current medicinal …, 2015 - ingentaconnect.com
Alzheimer's disease (AD) is a complex and progressive neurodegenerative disorder. The
available therapy is limited to the symptomatic treatment and its efficacy remains …

Polypharmacological properties and therapeutic potential of β-caryophyllene: a dietary phytocannabinoid of pharmaceutical promise

C Sharma, JM Al Kaabi, SM Nurulain… - Current …, 2016 - ingentaconnect.com
Background: β-Caryophyllene (BCP) is a natural bicyclic sesquiterpene abundantly found in
essential oils from various spices, fruits and medicinal as well as ornamental plants. It is …

Multi-target-directed ligands and other therapeutic strategies in the search of a real solution for Alzheimer's disease

A Agis-Torres, M Sollhuber… - Current …, 2014 - ingentaconnect.com
The lack of an adequate therapy for Alzheimer's Disease (AD) contributes greatly to the
continuous growing amount of papers and reviews, reflecting the important efforts made by …

[HTML][HTML] Δ9-THC-caused synaptic and memory impairments are mediated through COX-2 signaling

R Chen, J Zhang, N Fan, Z Teng, Y Wu, H Yang… - cell, 2013 - cell.com
Marijuana has been used for thousands of years as a treatment for medical conditions.
However, untoward side effects limit its medical value. Here, we show that synaptic and …

Cannabinoid and opioid interactions: implications for opiate dependence and withdrawal

JL Scavone, RC Sterling, EJ Van Bockstaele - Neuroscience, 2013 - Elsevier
Withdrawal from opiates, such as heroin or oral narcotics, is characterized by a host of
aversive physical and emotional symptoms. High rates of relapse and limited treatment …

A restricted population of CB1 cannabinoid receptors with neuroprotective activity

A Chiarlone, L Bellocchio, C Blázquez… - Proceedings of the …, 2014 - National Acad Sciences
The CB1 cannabinoid receptor, the main molecular target of endocannabinoids and
cannabis active components, is the most abundant G protein-coupled receptor in the …

[HTML][HTML] Cannabinoids in neurodegenerative disorders and stroke/brain trauma: from preclinical models to clinical applications

J Fernández-Ruiz, MA Moro, J Martínez-Orgado - Neurotherapeutics, 2015 - Elsevier
Cannabinoids form a singular family of plant-derived compounds (phytocannabinoids),
endogenous signaling lipids (endocannabinoids), and synthetic derivatives with multiple …