Myocardial ischemia is a disease with high morbidity and mortality, for which reperfusion is
currently the standard intervention. However, the reperfusion may lead to further myocardial …

Ischemia-reperfusion (IR) injury is central to the pathology of major cardiovascular diseases,
such as stroke and myocardial infarction. IR injury is mediated by several factors including …

Reperfusion injury, the paradoxical tissue response that is manifested by blood flow-
deprived and oxygen-starved organs following the restoration of blood flow and tissue …

The prototypical xanthine oxidase (XO) inhibitor allopurinol, has been the cornerstone of the
clinical management of gout and conditions associated with hyperuricemia for several …

Myocardial ischemia-reperfusion injury is an important cause of impaired heart function in
the early postoperative period subsequent to cardiac surgery. Reactive oxygen species …

Objective: We previously showed that brief intermittent ischemia applied during the onset of
reperfusion (ie, postconditioning) is cardioprotective in a canine model of ischemia …

Lack of blood supply or ischaemia underlies many of the most important cardiovascular and
cerebrovascular diseases faced by clinicians in their daily practice. Many of these ischaemic …

Myeloperoxidase (MPO) was used as a marker enzyme for measuring polymorphonuclear
leukocyte (PMN) accumulation in tissue samples. The MPO recovery from kidney, liver …

Recent evidence highlights monoamine oxidases (MAO) as another prominent source of
oxidative stress. MAO are a class of enzymes located in the outer mitochondrial membrane …

Myocardial ischemia is a major cause of morbidity and mortality in the world. Although
restoration of blood flow after prolonged ischemia is essential for cardiomyocytes salvation …