[HTML][HTML] Type 2 inflammation in eosinophilic esophagitis: from pathophysiology to therapeutic targets

F Racca, G Pellegatta, G Cataldo, E Vespa… - Frontiers in …, 2022 - frontiersin.org
Eosinophilic esophagitis (EoE) is a chronic immune-mediated disease of the esophagus
characterized clinically by symptoms related to esophageal dysfunction and histologically by …

Evidence-based treatments for eosinophilic esophagitis: insights for the clinician

S Feo-Ortega, AJ Lucendo - Therapeutic Advances in …, 2022 - journals.sagepub.com
Eosinophilic esophagitis (EoE) is a chronic inflammatory disorder characterized by
symptoms of esophageal dysfunction and eosinophil-predominant inflammation. Left …

Current treatment options and long-term outcomes in patients with eosinophilic esophagitis

AJ Lucendo, J Molina-Infante - Expert review of clinical …, 2022 - Taylor & Francis
Introduction Dietary and pharmacological (proton pump inhibitors, swallowed topical
corticosteroids) therapies are effective for induction of clinical and histological remission of …

EoE CONNECT, the European Registry of Clinical, Environmental, and Genetic Determinants in Eosinophilic Esophagitis: rationale, design, and study protocol of a …

AJ Lucendo, C Santander, E Savarino… - Therapeutic …, 2022 - journals.sagepub.com
Background: The growing prevalence of eosinophilic esophagitis (EoE) represents a
considerable burden to patients and health care systems. Optimizing cost-effective …

Role of mast cells in eosinophilic esophagitis

R Janarthanam, SM Bolton… - Current Opinion in …, 2022 - journals.lww.com
Mast cells appear to play a key role in eosinophilic esophagitis and serve as a biomarker of
mucosal healing in conjunction with eosinophils. Excessive mast cell activation likely …

Pharmacologic management of eosinophilic esophagitis

GW Falk, R Pesek - Immunology and Allergy Clinics, 2024 - immunology.theclinics.com
Medications, in addition to food elimination diets, are the mainstay of treatment for
eosinophilic esophagitis (EoE). The ultimate choice of therapy depends on shared decision …

Medication adherence rates in adolescents with eosinophilic esophagitis are low and are associated with health habits

P Mehta, Z Pan, W Zhou, BM Kwan… - Journal of pediatric …, 2023 - journals.lww.com
Although swallowed topical steroids are effective in inducing histological remission in
eosinophilic esophagitis (EoE), their efficacy is limited by treatment nonadherence. In this …

Mucoadhesive Budesonide Solution for the Treatment of Pediatric Eosinophilic Esophagitis

A Spennacchio, A Lopalco, GF Racaniello… - Pharmaceuticals, 2024 - mdpi.com
Eosinophilic Esophagitis is an antigen-mediated inflammatory disease characterized by
thickening of the esophageal wall, leading to dysphagia, vomiting, reflux, and abdominal …

Eosinophilic esophagitis and achalasia: two distinct nosologic entities or a possible etiopathogenic association?

D Schizas, A Syllaios, M Vailas, M Sotiropoulou… - Digestive …, 2021 - karger.com
Background: Despite the fact that researchers have made significant progress in elucidating
the pathophysiology of esophageal diseases, the understanding of esophageal motility …

Diagnosis and management of eosinophilic esophagitis in children: An update from the European Society for Paediatric Gastroenterology, Hepatology and Nutrition …

J Amil‐Dias, S Oliva, A Papadopoulou… - Journal of Pediatric …, 2024 - Wiley Online Library
Abstract Introduction Eosinophilic esophagitis (EoE) is a chronic inflammatory disease of the
esophagus characterized by symptoms of esophageal dysfunction and histologically by …