Persufflation (or gaseous oxygen perfusion) as a method of organ preservation

TM Suszynski, MD Rizzari, WE Scott III, LA Tempelman… - Cryobiology, 2012 - Elsevier
Improved preservation techniques have the potential to improve transplant outcomes by
better maintaining donor organ quality and by making more organs available for …

Persufflation—current state of play

AJ Buhagiar, L Freitas, WE Scott III - Transplantology, 2021 - mdpi.com
With the ever-increasing disparity between the number of patients waiting for organ
transplants and the number organs available, some patients are unable to receive life …

Metabolism of canine kidneys in anaerobic ischemia and in aerobic ischemia by persufflation with gaseous oxygen

W Isselhard, M Berger, H Denecke, J Witte, JH Fischer… - Pflügers Archiv, 1972 - Springer
The changes in the status of the adenylic acid-creatine phosphate system and in glycogen,
glucose, and lactate were investigated in canine kidneys during preservation in anaerobic …

A new simple method for optimal storage of ischemically damaged kidneys

JH Fischer, A Czerniak, U Hauer, W Isselhard… - …, 1978 - journals.lww.com
A NEW SIMPLE METHOD FOR OPTIMAL STORAGE OF ISCHEMICALLY DAMA... :
Transplantation A NEW SIMPLE METHOD FOR OPTIMAL STORAGE OF ISCHEMICALLY …

Reduction in nonparenchymal cell injury and vascular endothelial dysfunction after cold preservation of the liver by gaseous oxygen

T Minor, W Isselhard, H Klauke - Transplant International, 1996 - Wiley Online Library
Reintroduction of oxygen to previously anoxic tissue may result in severe cell injury (oxygen
paradox) and contribute to the so‐called reperfusion damage of is‐chemic organs. Our study …

The effects of allopurinol and SOD on lipid peroxidation and energy metabolism in the liver after ischemia in an aerobic/anaerobic persufflation

T Minor, W Isselhard, Y Yamamoto, M Obara, S Saad - Surgery Today, 1993 - Springer
This study was aimed at examining the vulnerability of the liver to oxygen-free radicals upon
reoxygenation after prolonged ischemia. Livers from male Wistar rats were first flushed with …

Recent developments in persufflation for organ preservation

CG Min, KK Papas - Current Opinion in Organ Transplantation, 2018 - journals.lww.com
Persufflation is a promising, relatively simple, preservation technique that enables improved
oxygenation, which provides protection and improvement in the graft condition during …

GASEOUS OXYGEN PERFUSION OF THE RENAL VESSELS AS AN ADJUNCT IN KIDNEY PRESERVATION1

H Ross, ML ESCOTT - Transplantation, 1979 - journals.lww.com
Gaseous oxygen perfusion of the stored kidney provides life-supporting renal function in
canine kidneys damaged by 30 min of warm ischaemia followed by cold storage for a total of …

Function and metabolism of canine kidneys after aerobic ischemia by retrograde persufflation with gaseous oxygen

W Isselhard, J Witte, H Denecke, M Berger… - Research in …, 1974 - Springer
Retrograde persufflation of ischemic kidneys of dogs via the renal vein with gaseous O 2
was evaluated as a method of kidney preservation (retrograde aerobic ischemia) and …

Retrograde oxygen persufflation of kidney–experiment on an animal

J Moláček, V Opatrný, R Matějka, J Baxa, V Třeška - in vivo, 2016 - iv.iiarjournals.org
Aim: There is still a lack of organs for transplantation purposes. In the field of kidney and liver
transplantation, one available solution is the use of organs from so-called marginal donors …