Thymoquinone: a review on its pharmacological importance, and its association with oxidative stress, COVID-19, and radiotherapy
Widely consumed worldwide, Nigella sativa (NS) is a medicinal herb commonly used in
various alternative medicine systems, such as Unani and Tibb, Ayurveda, and Siddha …
various alternative medicine systems, such as Unani and Tibb, Ayurveda, and Siddha …
Medicinal chemistry of indane and its analogues: A mini review
Abstract 'Indane′ and its analogues indene, 1‐indenone, and 1, 3‐indandione present an
attractive biological profile for the rational development of therapeutic molecules. The …
attractive biological profile for the rational development of therapeutic molecules. The …
Anticancer potential of natural peptides from terrestrial and marine environments: A review
M Eghtedari, SJ Porzani, B Nowruzi - Phytochemistry Letters, 2021 - Elsevier
Peptide-based therapies offer the potential opportunity for dangerous diseases such as
cancer. Anticancer peptide and their strategies to defend against cancer cell lines are found …
cancer. Anticancer peptide and their strategies to defend against cancer cell lines are found …
Exploring marine as a rich source of bioactive peptides: Challenges and opportunities from marine pharmacology
This review highlights the underexplored potential and promises of marine bioactive
peptides (MBPs) with unique structural, physicochemical, and biological activities to fight …
peptides (MBPs) with unique structural, physicochemical, and biological activities to fight …
Viral target and metabolism‐based rationale for combined use of recently authorized small molecule COVID‐19 medicines: Molnupiravir, nirmatrelvir, and remdesivir
D Yan, B Yan - Fundamental & Clinical Pharmacology, 2023 - Wiley Online Library
The COVID‐19 pandemic remains a major health concern worldwide, and SARS‐CoV‐2 is
continuously evolving. There is an urgent need to identify new antiviral drugs and develop …
continuously evolving. There is an urgent need to identify new antiviral drugs and develop …
Design, synthesis, biological evaluation and molecular docking of new 1, 3, 4-oxadiazole homonucleosides and their double-headed analogs as antitumor agents
A novel series of homonucleosides and their double-headed analogs containing
theophylline, 1, 3, 4-oxadiazole, and variant nucleobases was designed and synthesized …
theophylline, 1, 3, 4-oxadiazole, and variant nucleobases was designed and synthesized …
Synthesis of new imidazole-triazole-glycoside hybrids as anti-breast cancer candidates
WI El-Sofany, WA El-sayed, AA Abd-Rabou… - Journal of Molecular …, 2022 - Elsevier
One of the leading causes of death worldwide among women is breast cancer. Thus,
discovering new multi-target anti-breast cancer drugs is mandatory to stimulate nitric oxide …
discovering new multi-target anti-breast cancer drugs is mandatory to stimulate nitric oxide …
Nucleoside analogues: N-glycosylation methodologies, synthesis of antiviral and antitumor drugs and potential against drug-resistant bacteria and Alzheimer's …
C Maria, AP Rauter - Carbohydrate Research, 2023 - Elsevier
Nucleosides have gained significant attention since the discovery of the structure of DNA.
Nucleoside analogues may be synthesized through multiple synthetic pathways, however …
Nucleoside analogues may be synthesized through multiple synthetic pathways, however …
Synthesis and anticancer properties of 'azole'based chemotherapeutics as emerging chemical moieties: A comprehensive review
Azole frameworks serve as privileged scaffolds in the contemporary drug design paradigm
owing to their unique physicochemical profile that promotes the development of highly …
owing to their unique physicochemical profile that promotes the development of highly …
A Unified Strategy to Fluorinated Nucleoside Analogues Via an Electrophilic Manifold
AJ Neel, BWH Turnbull, WP Carson, T Benkovics… - Organic …, 2022 - ACS Publications
Herein, we present a strategy for the preparation of 3′-fluorinated nucleoside analogues
via the aminocatalytic, electrophilic fluorination of readily accessible and bench-stable 2 …
via the aminocatalytic, electrophilic fluorination of readily accessible and bench-stable 2 …