Hydrogel and nanomedicine‐based multimodal therapeutic strategies for spinal cord injury
P Yin, W Liang, B Han, Y Yang, D Sun, X Qu… - Small …, 2024 - Wiley Online Library
Spinal cord injury (SCI) is a severe neurodegenerative disease caused by mechanical and
biological factors, manifesting as a loss of motor and sensory functions. Inhibition of injury …
biological factors, manifesting as a loss of motor and sensory functions. Inhibition of injury …
Mesenchymal stem cell therapy in traumatic spinal cord injury: a systematic review
R Montoto-Meijide, R Meijide-Faílde… - International Journal of …, 2023 - mdpi.com
Recovery from a traumatic spinal cord injury (TSCI) is challenging due to the limited
regenerative capacity of the central nervous system to restore cells, myelin, and neural …
regenerative capacity of the central nervous system to restore cells, myelin, and neural …
CD44-targeting hyaluronic acid-selenium nanoparticles boost functional recovery following spinal cord injury
W Luo, Y Li, J Zhao, R Niu, C Xiang, M Zhang… - Journal of …, 2024 - Springer
Background Therapeutic strategies based on scavenging reactive oxygen species (ROS)
and suppressing inflammatory cascades are effective in improving functional recovery after …
and suppressing inflammatory cascades are effective in improving functional recovery after …
[HTML][HTML] Targeting mitochondrial oxidative stress: potential neuroprotective therapy for spinal cord injury
Z He, C Zhang, JX Liang, FF Zheng, XY Qi… - Journal of Integrative …, 2023 - imrpress.com
Spinal cord injury (SCI) is a serious central nervous system (CNS) injury disease related to
hypoxia-ischemia and inflammation. It is characterized by excessive reactive oxygen …
hypoxia-ischemia and inflammation. It is characterized by excessive reactive oxygen …
[HTML][HTML] Nanomaterials as therapeutic agents to modulate astrocyte-mediated inflammation in spinal cord injury
W Luo, Y Li, C Xiang, T Aizawa, R Niu, Y Wang… - Materials Today Bio, 2023 - Elsevier
Promoting the recovery of neurological function in patients with traumatic spinal cord injury
(TSCI) remains challenging. The balance between astrocyte-mediated neurotrophic and pro …
(TSCI) remains challenging. The balance between astrocyte-mediated neurotrophic and pro …
Association between Cerebrospinal Fluid and Serum Biomarker Levels and Diagnosis, Injury Severity, and Short-Term Outcomes in Patients with Acute Traumatic …
Z Yang, S Apiliogullari, Y Fu, A Istanbouli, S Kaur… - Diagnostics, 2023 - mdpi.com
Acute traumatic spinal cord injury (SCI) is recognized as a global problem that can lead to a
range of acute and secondary complications impacting morbidity and mortality. There is still …
range of acute and secondary complications impacting morbidity and mortality. There is still …
Development of BDNF/NGF/IKVAV Peptide Modified and Gold Nanoparticle Conductive PCL/PLGA Nerve Guidance Conduit for Regeneration of the Rat Spinal Cord …
Spinal cord injuries are very common worldwide, leading to permanent nerve function loss
with devastating effects in the affected patients. The challenges and inadequate results in …
with devastating effects in the affected patients. The challenges and inadequate results in …
Exosomes as therapeutic and drug delivery vehicle for neurodegenerative diseases
Neurodegenerative disorders are complex, progressive, and life-threatening. They cause
mortality and disability for millions of people worldwide. Appropriate treatment for …
mortality and disability for millions of people worldwide. Appropriate treatment for …
Improving Efficiency of Direct Pro-Neural Reprogramming: Much-Needed Aid for Neuroregeneration in Spinal Cord Injury
DA Chudakova, EM Samoilova, VP Chekhonin… - Cells, 2023 - mdpi.com
Spinal cord injury (SCI) is a medical condition affecting~ 2.5–4 million people worldwide.
The conventional therapy for SCI fails to restore the lost spinal cord functions; thus, novel …
The conventional therapy for SCI fails to restore the lost spinal cord functions; thus, novel …
Current multi-scale biomaterials for tissue regeneration following spinal cord injury
Y ang Zhang, Z huan Wu, J feng Wu, T dong Li… - Neurochemistry …, 2024 - Elsevier
Spinal cord injury (SCI) may cause loss of motor and sensory function, autonomic
dysfunction, and thus disrupt the quality of life of patients, leading to severe disability and …
dysfunction, and thus disrupt the quality of life of patients, leading to severe disability and …