Bronchopulmonary dysplasia from chest radiographs to magnetic resonance imaging and computed tomography: adding value

NS Higano, AJ Bates, CC Gunatilaka, EB Hysinger… - Pediatric …, 2022 - Springer
Bronchopulmonary dysplasia (BPD) is a common long-term complication of preterm birth.
The chest radiograph appearance and survivability have evolved since the first description …

Outpatient respiratory management of infants, children, and adolescents with post-prematurity respiratory disease: an official American Thoracic Society clinical …

AI Cristea, CL Ren, R Amin, LC Eldredge… - American journal of …, 2021 - atsjournals.org
Background: Premature birth affects millions of neonates each year, placing them at risk for
respiratory disease due to prematurity. Bronchopulmonary dysplasia is the most common …

Modern pulmonary imaging of bronchopulmonary dysplasia

NS Higano, JL Ruoss, JC Woods - Journal of Perinatology, 2021 - nature.com
Bronchopulmonary dysplasia (BPD) is a complex and serious cardiopulmonary morbidity in
infants who are born preterm. Despite advances in clinical care, BPD remains a significant …

Increased work of breathing due to tracheomalacia in neonates

CC Gunatilaka, NS Higano, EB Hysinger… - Annals of the …, 2020 - atsjournals.org
Rationale: Dynamic collapse of the tracheal lumen (tracheomalacia) occurs frequently in
premature neonates, particularly in those with common comorbidities such as …

Ultrashort echo-time MRI for the assessment of tracheomalacia in neonates

EB Hysinger, AJ Bates, NS Higano, D Benscoter… - Chest, 2020 - Elsevier
Background Bronchoscopy is the gold standard for evaluating tracheomalacia; however,
reliance on an invasive procedure limits understanding of normal airway dynamics. Self …

Three-dimensional ultrashort echo time MRI for functional lung imaging in cystic fibrosis

JF Heidenreich, AM Weng, C Metz, T Benkert… - Radiology, 2020 - pubs.rsna.org
Background In cystic fibrosis (CF), recurrent imaging and pulmonary function tests (PFTs)
are needed for the assessment of lung function during disease management. Purpose To …

Image Phenotyping of Preterm-Born Children Using Hyperpolarized 129Xe Lung Magnetic Resonance Imaging and Multiple-Breath Washout

HF Chan, LJ Smith, AM Biancardi, J Bray… - American Journal of …, 2023 - atsjournals.org
Rationale: Preterm birth is associated with low lung function in childhood, but little is known
about the lung microstructure in childhood. Objectives: We assessed the differential …

The effect of airway motion and breathing phase during imaging on CFD simulations of respiratory airflow

CC Gunatilaka, A Schuh, NS Higano, JC Woods… - Computers in biology …, 2020 - Elsevier
Rationale Computational fluid dynamics (CFD) simulations of respiratory airflow can quantify
clinically useful information that cannot be obtained directly, such as the work of breathing …

Imaging in neonatal respiratory disease

EB Hysinger, NS Higano, PJ Critser… - Paediatric respiratory …, 2022 - Elsevier
The purpose of this review is to describe the current state of the art in clinical imaging for
NICU patients, divided into major areas that correspond to likely phenotypes of neonatal …

Magentic Resonance Imaging Evaluation of Regional Lung Vts in Severe Neonatal Bronchopulmonary Dysplasia

KR Gouwens, NS Higano, KT Marks… - American Journal of …, 2020 - atsjournals.org
Rationale: Bronchopulmonary dysplasia is a heterogeneous lung disease characterized by
regions of cysts and fibrosis, but methods for evaluating lung function are limited to whole …