Evidence supporting the use of probiotics for the prevention and treatment of chemotherapy-induced intestinal mucositis

LD Prisciandaro, MS Geier, RN Butler… - Critical reviews in …, 2011 - Taylor & Francis
Although chemotherapy remains the current best practice for the treatment of neoplasia, the
severity of its associated side-effects continues to impact detrimentally on the quality of life …

[HTML][HTML] The gut microbiome can be used to predict the gastrointestinal response and efficacy of lung cancer patients undergoing chemotherapy

M Zhang, H Zhou, S Xu, D Liu, Y Cheng… - Annals of Palliative …, 2020 - apm.amegroups.org
Background: Lung cancer has the highest incidence and mortality rate of any cancer
worldwide. Platinum-based combination chemotherapy is still the standard treatment for …

Amelioration of 5-fluorouracil-induced intestinal mucositis by Streptococcus thermophilus ST4 in a mouse model

SR Shen, WJ Chen, HF Chu, SH Wu, YR Wang… - PLoS …, 2021 - journals.plos.org
Intestinal mucositis is a commonly encountered toxic side effect in patients undergoing 5-
fluorouracil (5-FU)-based chemotherapy. Numerous studies have shown that probiotics …

The future of microbiome‐based therapeutics in clinical applications

A Sharma, P Das, M Buschmann… - Clinical Pharmacology …, 2020 - Wiley Online Library
The microbiome, a collection of microorganisms, their genomes, and the surrounding
environmental conditions, is akin to a human organ, and knowledge is emerging on its role …

Anti-inflammatory effects of Radix Aucklandiae herbal preparation ameliorate intestinal mucositis induced by 5-fluorouracil in mice

JH Liu, CH Hsieh, CY Liu, CW Chang, YJ Chen… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance 5-Fluorouracil (5-FU) is a chemotherapy agent
that is widely used in clinical oncologic practice. However, intestinal mucositis is the most …

Probiotics for preventive health

A Minocha - Nutrition in Clinical Practice, 2009 - Wiley Online Library
Gut flora and probiotics have potential to affect health and disease far beyond the gut. There
is increasing evidence that probiotics have beneficial effects in preventing a wide range of …

β-Patchoulene Ameliorates Water Transport and the Mucus Barrier in 5-Fluorouracil-Induced Intestinal Mucositis Rats via the cAMP/PKA/CREB Signaling Pathway

J Wu, Y Gan, H Luo, N Xu, L Chen, M Li… - Frontiers in …, 2021 - frontiersin.org
Intestinal mucositis (IM) is the main side effect observed in patients who receive cancer
chemotherapy. The characteristics of ulceration, vomiting, and severe diarrhea cause …

Bowel radiation injury: complexity of the pathophysiology and promises of cell and tissue engineering

L Moussa, B Usunier, C Demarquay… - Cell …, 2016 - journals.sagepub.com
Ionizing radiation is effective to treat malignant pelvic cancers, but the toxicity to surrounding
healthy tissue remains a substantial limitation. Early and late side effects not only limit the …

Mechanisms of TKI-induced diarrhea in cancer patients

JM Bowen - Current opinion in supportive and palliative care, 2013 - journals.lww.com
Mechanisms of TKI-induced diarrhea in cancer patients : Current Opinion in Supportive and
Palliative Care Mechanisms of TKI-induced diarrhea in cancer patients : Current Opinion in …

Akkermansia muciniphila and its outer membrane protein Amuc_1100 prophylactically attenuate 5-fluorouracil-induced intestinal mucositis

S Chen, K Qian, G Zhang, M Zhang - Biochemical and biophysical research …, 2022 - Elsevier
Fluorouracil (5-FU) is a chemotherapy drug used to treat tumors. Previous studies have
shown that Akkermansia muciniphila (A. muciniphila) and its outer membrane protein …