Poly (lactic acid)-based microparticles for drug delivery applications: An overview of recent advances

A Vlachopoulos, G Karlioti, E Balla, V Daniilidis… - Pharmaceutics, 2022 - mdpi.com
The sustained release of pharmaceutical substances remains the most convenient way of
drug delivery. Hence, a great variety of reports can be traced in the open literature …

Nanomaterials in tumor immunotherapy: new strategies and challenges

X Zhu, S Li - Molecular Cancer, 2023 - Springer
Tumor immunotherapy exerts its anti-tumor effects by stimulating and enhancing immune
responses of the body. It has become another important modality of anti-tumor therapy with …

Glass transition temperature of PLGA particles and the influence on drug delivery applications

G Liu, K McEnnis - Polymers, 2022 - mdpi.com
Over recent decades, poly (lactic-co-glycolic acid)(PLGA) based nano-and micro-drug
delivery vehicles have been rapidly developed since PLGA was approved by the Food and …

Strategies for overcoming protein and peptide instability in biodegradable drug delivery systems

M Shi, KJ McHugh - Advanced Drug Delivery Reviews, 2023 - Elsevier
The global pharmaceutical market has recently shifted its focus from small molecule drugs to
peptide, protein, and nucleic acid drugs, which now comprise a majority of the top-selling …

Long-acting parenteral drug delivery systems for the treatment of chronic diseases

AB Jindal, AR Bhide, S Salave, D Rana… - Advanced Drug Delivery …, 2023 - Elsevier
The management of chronic conditions often requires patients to take daily medication for an
extended duration. However, the need for daily dosing can lead to nonadherence to the …

The recent advancement in the PLGA-based thermo-sensitive hydrogel for smart drug delivery

F Rahmani, R Atabaki, S Behrouzi… - International Journal of …, 2023 - Elsevier
To date, hydrogels have opened new prospects for potential applications for drug delivery.
The thermo-sensitive hydrogels have the great potential to provide more effective and …

Prodrug approaches for the development of a long-acting drug delivery systems

ST Chien, IT Suydam, KA Woodrow - Advanced Drug Delivery Reviews, 2023 - Elsevier
Long-acting formulations are designed to reduce dosing frequency and simplify dosing
schedules by providing an extended duration of action. One approach to obtain long-acting …

Special features of polyester-based materials for medical applications

RN Darie-Niță, M Râpă, S Frąckowiak - Polymers, 2022 - mdpi.com
This article presents current possibilities of using polyester-based materials in hard and soft
tissue engineering, wound dressings, surgical implants, vascular reconstructive surgery …

Microcarriers in application for cartilage tissue engineering: Recent progress and challenges

SL Ding, X Liu, XY Zhao, KT Wang, W Xiong, ZL Gao… - Bioactive Materials, 2022 - Elsevier
Successful regeneration of cartilage tissue at a clinical scale has been a tremendous
challenge in the past decades. Microcarriers (MCs), usually used for cell and drug delivery …

Current trends in PLGA based long-acting injectable products: The industry perspective

OS Muddineti, A Omri - Expert Opinion on Drug Delivery, 2022 - Taylor & Francis
Introduction Poly (lactic-co-glycolic acid)(PLGA) has been used in many long-acting drug
formulations, which have been approved by the US Food and Drug Administration (FDA) …