Wnt signaling in orofacial clefts: crosstalk, pathogenesis and models
K Reynolds, P Kumari… - Disease models & …, 2019 - journals.biologists.com
Diverse signaling cues and attendant proteins work together during organogenesis,
including craniofacial development. Lip and palate formation starts as early as the fourth …
including craniofacial development. Lip and palate formation starts as early as the fourth …
Grainyhead-like (Grhl) target genes in development and cancer
JG Gasperoni, JN Fuller, C Darido… - International Journal of …, 2022 - mdpi.com
Grainyhead-like (GRHL) factors are essential, highly conserved transcription factors (TFs)
that regulate processes common to both natural cellular behaviours during embryogenesis …
that regulate processes common to both natural cellular behaviours during embryogenesis …
Structural basis of gene regulation by the Grainyhead/CP2 transcription factor family
Q Ming, Y Roske, A Schuetz, K Walentin… - Nucleic acids …, 2018 - academic.oup.com
Abstract Grainyhead (Grh)/CP2 transcription factors are highly conserved in multicellular
organisms as key regulators of epithelial differentiation, organ development and skin barrier …
organisms as key regulators of epithelial differentiation, organ development and skin barrier …
Spotlight on the granules (Grainyhead-like proteins)–from an evolutionary conserved controller of epithelial trait to pioneering the chromatin landscape
V Sundararajan, QY Pang, M Choolani… - Frontiers in Molecular …, 2020 - frontiersin.org
Among the transcription factors that are conserved across phylogeny, the grainyhead family
holds vital roles in driving the epithelial cell fate. In Drosophila, the function of grainyhead …
holds vital roles in driving the epithelial cell fate. In Drosophila, the function of grainyhead …
Mis-expression of grainyhead-like transcription factors in zebrafish leads to defects in enveloping layer (EVL) integrity, cellular morphogenesis and axial extension
The grainyhead-like (grhl) transcription factors play crucial roles in craniofacial
development, epithelial morphogenesis, neural tube closure, and dorso-ventral patterning …
development, epithelial morphogenesis, neural tube closure, and dorso-ventral patterning …
Grainyhead-like transcription factors in craniofacial development
MR Carpinelli, ME De Vries… - Journal of Dental …, 2017 - journals.sagepub.com
Craniofacial development in vertebrates involves the coordinated growth, migration, and
fusion of several facial prominences during embryogenesis, processes governed by strict …
fusion of several facial prominences during embryogenesis, processes governed by strict …
Meta-Analysis of Grainyhead-Like Dependent Transcriptional Networks: A Roadmap for Identifying Novel Conserved Genetic Pathways
N Mathiyalagan, LB Miles, PJ Anderson, T Wilanowski… - Genes, 2019 - mdpi.com
The Drosophila grainyhead (grh) and vertebrate Grainyhead-like (Grhl) transcription factors
are among the most critical genes for epithelial development, maintenance and …
are among the most critical genes for epithelial development, maintenance and …
Soft-tissue differentiation and bone densitometry via energy-discriminating X-ray microCT
X-ray computed tomography (CT) is an important diagnostic tool in medicine as well as
being an essential research technique for animal imaging and bioscience. The key aim of …
being an essential research technique for animal imaging and bioscience. The key aim of …
Interrogating the Grainyhead-like 2 (Grhl2) genomic locus identifies an enhancer element that regulates palatogenesis in mouse
M de Vries, M Carpinelli, E Rutland, A Hatzipantelis… - Developmental …, 2020 - Elsevier
The highly-conserved Grainyhead-like (Grhl) transcription factors are critical regulators of
embryogenesis that regulate cellular survival, proliferation, migration and epithelial integrity …
embryogenesis that regulate cellular survival, proliferation, migration and epithelial integrity …
Grainyhead‐like 3 (Grhl3) deficiency in brain leads to altered locomotor activity and decreased anxiety‐like behaviors in aged mice
S Dworkin, A Auden, DD Partridge… - Developmental …, 2017 - Wiley Online Library
The highly conserved Grainyhead‐like (Grhl) family of transcription factors, comprising three
members in vertebrates (Grhl1‐3), play critical regulatory roles during embryonic …
members in vertebrates (Grhl1‐3), play critical regulatory roles during embryonic …