Major depressive disorder (MDD) is a multifactorial and polygenic disorder, where multiple
and partially overlapping sets of susceptibility genes interact each other and with the …

We survey studies which relate abnormal neurogenesis to major depressive disorder.
Clinically, descriptive gene and protein expression analysis and genetic and functional …

In the clinic selective serotonin reuptake inhibitors (SSRIs), like Fluoxetine, remain the
primary treatment for major depression. It has been suggested that miR-16 regulates …

Major Depressive Disorder (MDD) represents a major global health concern, a body-mind
malady of rising prevalence worldwide nowadays. The complex network of mechanisms …

Background Neurotrophins including brain-derived neurotropic factor (BDNF) are implicated
in the pathogenesis of major depressive disorder (MDD). Yet, the roles of brain-specific …

Background Major depression is a prevalent mood disorder. Chronic stress is presumably
main etiology that leads to the neuron and synapse atrophies in the limbic system. However …

Despite significant research efforts aimed at understanding the neurobiological
underpinnings of mood (depression, bipolar disorder) and psychotic disorders, the …

Dysregulation of microRNA (miRNA) has been shown to be involved in early observations of
depression. MicroRNA-124-3p (miR-124) is the most abundant microRNA in the brain …

Aims Several studies have reported the role of biomarkers either in diabetes or depression.
The present study is aimed at profiling the circulating levels of miR-128, brain-derived …

Background Major depressive disorder (MDD) is a common debilitating disease of unknown
etiology. The expression of miRNA is closely related to depression and efficacy of …