Objective Use of the frailty index to measure an accumulation of deficits has been proven a
valuable method for identifying elderly people at risk for increased vulnerability, disease …

Cardiovascular diseases (CVDs) remain a leading cause of death worldwide. Among the
major risk factors for CVD, obesity and diabetes mellitus have received considerable …

During the periparturient period, lipolysis in adipose tissue (AT) mobilizes fatty acid reserves
to meet high energy needs of dairy cows. This physiological response is accompanied by …

Nonalcoholic fatty liver disease (NAFLD) has become a leading cause of chronic liver
diseases globally. NAFLD includes a range of hepatic manifestations, starting with liver …

Obesity and diabetes are closely related metabolic disorders that have become major public
health concerns worldwide. Over the past few decades, numerous studies have explored the …

Evidence about the relevance of the complement system, a highly conserved constituent of
the innate immunity response that orchestrates the elimination of pathogens and the …

Non‐alcoholic fatty liver disease (NAFLD) is a growing public health threat and becoming
the leading cause of liver transplantation. Nevertheless, no approved specific treatment is …

Background Chronic inflammation is a factor in the pathogenesis of sarcopenia, which is
characterized by low muscle mass and reduced strength. Complement C3 is important in the …

Adipose tissue, as an endocrine organ, secretes several adipocyte‐derived hormones
named 'adipokines' that are implicated in regulating energy haemostasis. Substantial …

Objectives Diabetes aggravates the risk and severity of periodontitis, but the specific
mechanism remains confused. Complement 3 (C3) is closely related to complications of type …