Navigating the fungal polyketide chemical space: from genes to molecules
The iterative type I polyketide synthases (IPKSs) are central to the biosynthesis of an
enormously diverse array of natural products in fungi. These natural products, known as …
enormously diverse array of natural products in fungi. These natural products, known as …
Exploiting the mosaic structure of trans-acyltransferase polyketide synthases for natural product discovery and pathway dissection
TA Nguyen, K Ishida, H Jenke-Kodama… - Nature …, 2008 - nature.com
Modular polyketide synthases (PKSs) are giant bacterial enzymes that synthesize many
polyketides of therapeutic value. In contrast to PKSs that provide acyltransferase (AT) …
polyketides of therapeutic value. In contrast to PKSs that provide acyltransferase (AT) …
Comparative Genome Structure, Secondary Metabolite, and Effector Coding Capacity across Cochliobolus Pathogens
The genomes of five Cochliobolus heterostrophus strains, two Cochliobolus sativus strains,
three additional Cochliobolus species (Cochliobolus victoriae, Cochliobolus carbonum …
three additional Cochliobolus species (Cochliobolus victoriae, Cochliobolus carbonum …
The evolution of fungal metabolic pathways
Fungi contain a remarkable range of metabolic pathways, sometimes encoded by gene
clusters, enabling them to digest most organic matter and synthesize an array of potent small …
clusters, enabling them to digest most organic matter and synthesize an array of potent small …
Evolutionary implications of bacterial polyketide synthases
H Jenke-Kodama, A Sandmann… - Molecular biology …, 2005 - academic.oup.com
Polyketide synthases (PKS) perform a stepwise biosynthesis of diverse carbon skeletons
from simple activated carboxylic acid units. The products of the complex pathways possess a …
from simple activated carboxylic acid units. The products of the complex pathways possess a …
Secondary metabolites from entomopathogenic Hypocrealean fungi
I Molnár, DM Gibson, SB Krasnoff - Natural product reports, 2010 - pubs.rsc.org
Covering: up to the end of February 2010 This review surveys the natural products
described from entomopathogenic Hypocrealean fungi, including their structures, biological …
described from entomopathogenic Hypocrealean fungi, including their structures, biological …
Two Separate Gene Clusters Encode the Biosynthetic Pathway for the Meroterpenoids Austinol and Dehydroaustinol in Aspergillus nidulans
Meroterpenoids are a class of fungal natural products that are produced from polyketide and
terpenoid precursors. An understanding of meroterpenoid biosynthesis at the genetic level …
terpenoid precursors. An understanding of meroterpenoid biosynthesis at the genetic level …
Metabolic diversity of lichen-forming ascomycetous fungi: culturing, polyketide and shikimate metabolite production, and PKS genes
E Stocker-Wörgötter - Natural product reports, 2008 - pubs.rsc.org
Covering: 2001 to 2007 Lichens are composite and symbiotic organisms. Biologically, they
often have been interpreted as one organism (fungi and algae associated within a common …
often have been interpreted as one organism (fungi and algae associated within a common …
Lateral gene transfer in eukaryotes
JO Andersson - Cellular and Molecular Life Sciences CMLS, 2005 - Springer
Lateral gene transfer–the transfer of genetic material between species–has been
acknowledged as a major mechanism in prokaryotic genome evolution for some time …
acknowledged as a major mechanism in prokaryotic genome evolution for some time …
A Putative Polyketide Synthase/Peptide Synthetase from Magnaporthe grisea Signals Pathogen Attack to Resistant Rice
HU Böhnert, I Fudal, W Dioh, D Tharreau… - The Plant …, 2004 - academic.oup.com
Isolates of the rice blast fungus Magnaporthe grisea that carry the gene encoding Avirulence
Conferring Enzyme1 (ACE1) are specifically recognized by rice (Oryza sativa) cultivars …
Conferring Enzyme1 (ACE1) are specifically recognized by rice (Oryza sativa) cultivars …