Galanin in normal and hyperplastic anterior pituitary cells: from pituitary tumor cell lines to transgenic mice

JF Hyde, JP MOORE JR, A Cai - … of the New York Academy of …, 1998 - Wiley Online Library
Studies on the regulation of galanin expression in the epithelial cells of the anterior pituitary
gland have provided a wealth of insight into the cellular and molecular biology of this unique …

Negative regulation of N-cadherin-mediated cell-cell adhesion by the estrogen receptor signaling pathway in rat pituitary GH3 cells

CA Heinrich, MR Lail-Trecker, JJ Peluso, BA White - Endocrine, 1999 - Springer
The ability of the estrogen receptor signaling pathway to regulate cell-cell adhesion, and N-
cadherin and β-catenin expression was examined in rat somatolactotropic GH 3 cells …

Structural organization and chromosomal localization of three human galanin receptor genes

TP Iismaa, Z Fathi, YJ Hort, LG Iben… - Annals of the New …, 1998 - Wiley Online Library
Human galanin receptor subtypes GALR1, GALR2, and GALR3 are encoded by separate
genes that are located on human chromosomes 18q23, 17q25. 3, and 22q13. 1 …

Galanin within the normal and hyperplastic anterior pituitary gland: localization, secretion, and functional analysis in normal and human growth hormone-releasing …

JP Moore Jr, A Cai, BE Maley, L Jennes… - Endocrinology, 1999 - academic.oup.com
Studies evaluating estrogen-induced anterior pituitary tumors revealed a strong direct
correlation between expression of the peptide galanin and tumor growth. To evaluate further …

Galanin-like immunoreactive nerve fibres in the anterior pituitary of the normal and adrenalectomized rat

YY Liu, G Ju - Acta histochemica, 1998 - Elsevier
Our previous studies have shown the presence of substantial amounts of substance P and
calcitonin gene-related peptide-like immunoreactive nerve fibres in the anterior pituitary of …

Regulation of anterior pituitary galanin gene expression by thyroid hormone

SC Hooi, JI Koenig, DR Abraczinskas… - Molecular brain …, 1997 - Elsevier
Thyroid hormone is required for basal and estrogen-induced expression of anterior pituitary
galanin. Steady-state anterior pituitary galanin mRNA levels decreased 6-fold in hypothyroid …

The differential effects of galanin-(1—30) and-(3—30) on anterior pituitary hormone secretion in vivo in humans

JF Todd, CMB Edwards, MA Ghatei… - American Journal of …, 2000 - journals.physiology.org
Intravenous injection of galanin increases plasma growth hormone (GH) and prolactin (PRL)
concentrations. In the rat, the effects of galanin on GH appear to be mediated via the …

Sex‐steroid control of galanin in the rat hypothalamic‐pituitary axis

PL Selvais, JF Denef, E Adam… - Journal of …, 1995 - Wiley Online Library
To further investigate how sex steroids regulate galanin (GAL) in the rat pituitary and
hypothalamus, we examined the effects of prepubertal gonadectomy (Gx) and long‐term (9 …

Galanin and its three receptors in human pituitary adenoma

R Tofighi, S Barde, M Palkovits, A Höög, T Hökfelt… - Neuropeptides, 2012 - Elsevier
Galanin, a 29-aminoacid peptide (30 in humans), is widely distributed in the nervous and
endocrine systems and exerts its actions via three G-protein-coupled receptors, GalR1–3 …

In Vitro Effects of Oestradiol on Galanin Gene Expression in Rat Anterior Pituitary Cells

M Ponchon, P Lause, D Maiter - Journal of Neuroendocrinology, 2000 - Wiley Online Library
While the pituitary galanin gene is highly responsive to oestrogen stimulation in vivo, in vitro
effects of oestrogens on pituitary galanin gene expression have been less studied. We …