Detection of the 'big five'mold killers of humans: Aspergillus, Fusarium, Lomentospora, Scedosporium and Mucormycetes

CR Thornton - Advances in applied microbiology, 2020 - Elsevier
Fungi are an important but frequently overlooked cause of morbidity and mortality in
humans. Life-threatening fungal infections mainly occur in immunocompromised patients …

Molecular mechanisms that govern infection and antifungal resistance in Mucorales

C Lax, FE Nicolás, E Navarro… - … and Molecular Biology …, 2024 - Am Soc Microbiol
SUMMARY The World Health Organization has established a fungal priority pathogens list
that includes species critical or highly important to human health. Among them is the order …

Structural polymorphism of chitin and chitosan in fungal cell walls from solid-state NMR and principal component analysis

LD Fernando, MC Dickwella Widanage… - Frontiers in Molecular …, 2021 - frontiersin.org
Chitin is a major carbohydrate component of the fungal cell wall and a promising target for
novel antifungal agents. However, it is technically challenging to characterize the structure of …

A bacterial endosymbiont of the fungus Rhizopus microsporus drives phagocyte evasion and opportunistic virulence

H Itabangi, PCS Sephton-Clark, DP Tamayo, X Zhou… - Current biology, 2022 - cell.com
Opportunistic infections by environmental fungi are a growing clinical problem, driven by an
increasing population of people with immunocompromising conditions. Spores of the …

Bioengineered nanospores selectively blocking LC3-associated phagocytosis in tumor-associated macrophages potentiate antitumor immunity

Y Shang, H Lu, L Liao, S Li, H Xiong, J Yao - ACS nano, 2023 - ACS Publications
Although cytotoxic treatments hold tremendous potential in boosting antitumor immunity,
efferocytosis of tumor-associated macrophages (TAMs) could negatively remove apoptotic …

[HTML][HTML] Turning food waste to antibacterial and biocompatible fungal chitin/chitosan monofilaments

SE Svensson, AO Oliveira, KH Adolfsson… - International Journal of …, 2022 - Elsevier
Here, cell wall of a zygomycete fungus, Rhizopus delemar, grown on bread waste was wet
spun into monofilaments. Using the whole cell wall material omits the common chitosan …

Turning inside out: filamentous fungal secretion and its applications in biotechnology, agriculture, and the clinic

TC Cairns, X Zheng, P Zheng, J Sun, V Meyer - Journal of Fungi, 2021 - mdpi.com
Filamentous fungi are found in virtually every marine and terrestrial habitat. Vital to this
success is their ability to secrete a diverse range of molecules, including hydrolytic enzymes …

Iron assimilation during emerging infections caused by opportunistic fungi with emphasis on Mucorales and the development of antifungal resistance

FA Stanford, K Voigt - Genes, 2020 - mdpi.com
Iron is a key transition metal required by most microorganisms and is prominently utilised in
the transfer of electrons during metabolic reactions. The acquisition of iron is essential and …

COVID-19 associated mucormycosis: evolving technologies for early and rapid diagnosis

R Samson, M Dharne - 3 Biotech, 2022 - Springer
The post-coronavirus disease (COVID-19) mucormycosis is a deadly addition to the
pandemic spectrum. Although it'sa rare, aggressive, and opportunistic disease, the …

Serine/threonine phosphatase calcineurin orchestrates the intrinsic resistance to micafungin in the human-pathogenic fungus Mucor circinelloides

A Garcia, EY Huh, SC Lee - Antimicrobial Agents and …, 2023 - Am Soc Microbiol
Procedures such as solid-organ transplants and cancer treatments can leave many patients
in an immunocompromised state. This leads to their increased susceptibility to opportunistic …