Although the link between blood coagulation and atherogenesis has been long postulated,
only recently, and through the extensive work on transgenic mice, crossbred on an …

Cardiovascular disease (CVD) is the major determining factor of morbidity and mortality in
type 2 diabetic patients. The established relationship between type 2 diabetes and …

Abdominal aortic aneurysm (AAA) is a prevalent and potentially life threatening disease.
Many animal models have been developed to simulate the natural history of the disease or …

Mice are widely used to study arterial disease in humans, and the pathogenesis of arterial
diseases is known to be strongly influenced by hemodynamic factors. It is, therefore, of …

Objective—A solid body of evidence supports a role of extracellular ATP and its P2 receptors
in innate and adaptive immunity. It promotes inflammation as a danger signal in various …

The cardiovascular complications of obesity have prompted interest in dietary interventions
to reduce weight, including low-carbohydrate diets that are generally high in protein and fat …

Watermelon (Citrullus lanatus or C. lanatus) has many potentially bioactive compounds
including citrulline, which may influence atherosclerosis. In this study, we determined the …

Recent clinical data indicates that hemodynamic changes caused by cardiovascular
diseases such as atherosclerosis, heart failure, and hypertension affect cognition. Yet, the …

Objectives This study sought to examine the effects and underlying mechanisms of systemic
VEGF inhibition in experimental atherosclerosis and aortic endothelial cells. Background …

The pathogenesis of atherosclerosis involves dysfunctions of vascular endothelial cells and
smooth muscle cells as well as blood borne inflammatory cells such as monocyte-derived …