The presence of different APOE isoforms represents a well-known risk factor for
cardiovascular diseases. Besides the pleiotropic effects of APOE polymorphism on heart …

Hurler syndrome (mucopolysaccharidosis type I [MPS I]) is a uniformly lethal autosomal
recessive storage disease caused by absence of the enzyme α-l-iduronidase (IDUA), which …

Several lines of evidence suggest that antioxidant processes and (or) endogenous
antioxidants inhibit proatherogenic events in the blood vessel wall. Heme oxygenase (HO) …

Objective To characterize modifications of high‐density lipoprotein (HDL) in autoimmune gld
mice that may be relevant to premature atherosclerosis in systemic lupus erythematosus …

Objective—Fcγ receptors (FcγRs) are classified as activating (FcγRI, III, and IV) and
inhibitory (FcγRII) receptors. We have reported that deletion of activating FcγRs in …

Objective—Endothelial cells are central to the initiation of atherosclerosis, yet there has
been limited success in studying their gene expression in the mouse aorta. To address this …

Capture and representation of scientific knowledge in a structured format are essential to
improve the understanding of biological mechanisms involved in complex diseases …

BACKGROUND: Non-invasive methods of evaluating atherosclerosis in humans and
experimental animals are needed. Studies indicate that FDG-PET has a potential to detect …

Background Non-alcoholic fatty liver disease (NAFLD), an emerging public health problem,
may be a highly atherogenic condition. But the relationship between fatty liver diseases and …

The pulp of jussara açaí (Euterpe edulis Martius) fruit is rich in anthocyanins that exert
antioxidant and anti-inflammatory effects similar to those exerted by aerobic exercise. In the …