[HTML][HTML] Inflammation and immune dysfunction in Parkinson disease
Parkinson disease (PD) is a progressive neurodegenerative disease that affects peripheral
organs as well as the central nervous system and involves a fundamental role of …
organs as well as the central nervous system and involves a fundamental role of …
[HTML][HTML] Smelling the disease: Diagnostic potential of breath analysis
Breath analysis is a relatively recent field of research with much promise in scientific and
clinical studies. Breath contains endogenously produced volatile organic components …
clinical studies. Breath contains endogenously produced volatile organic components …
Dermoscopy, with and without visual inspection, for diagnosing melanoma in adults
Background Melanoma has one of the fastest rising incidence rates of any cancer. It
accounts for a small percentage of skin cancer cases but is responsible for the majority of …
accounts for a small percentage of skin cancer cases but is responsible for the majority of …
The versatile use of exhaled volatile organic compounds in human health and disease
AW Boots, JJBN van Berkel, JW Dallinga… - Journal of breath …, 2012 - iopscience.iop.org
Exhaled breath contains thousands of volatile organic compounds (VOCs) of which the
composition varies depending on health status. Various metabolic processes within the …
composition varies depending on health status. Various metabolic processes within the …
Exhaled volatile organic compounds identify patients with colorectal cancer
DF Altomare, M Di Lena, F Porcelli… - Journal of British …, 2013 - academic.oup.com
Background An effective screening tool for colorectal cancer is still lacking. Analysis of the
volatile organic compounds (VOCs) linked to cancer is a new frontier in cancer screening, as …
volatile organic compounds (VOCs) linked to cancer is a new frontier in cancer screening, as …
[HTML][HTML] Detection of cancer through exhaled breath: a systematic review
A Krilaviciute, JA Heiss, M Leja, J Kupcinskas… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Background Timely diagnosis of cancer represents a challenging task; in particular, there is
a need for reliable non-invasive screening tools that could achieve high levels of adherence …
a need for reliable non-invasive screening tools that could achieve high levels of adherence …
[HTML][HTML] Investigation of VOCs associated with different characteristics of breast cancer cells
The efficacy of breath volatile organic compounds (VOCs) analysis for the screening of
patients bearing breast cancer lesions has been demonstrated by using gas …
patients bearing breast cancer lesions has been demonstrated by using gas …
Detection of volatile organic compounds as biomarkers in breath analysis by different analytical techniques
B Buszewski, D Grzywinski, T Ligor, T Stacewicz… - Bioanalysis, 2013 - Taylor & Francis
Breath is a rich mixture containing numerous volatile organic compounds at trace amounts
(ppbv–pptv level) such as: hydrocarbons, alcohols, ketones, aldehydes, esters or …
(ppbv–pptv level) such as: hydrocarbons, alcohols, ketones, aldehydes, esters or …
[HTML][HTML] Real-time mass spectrometric identification of metabolites characteristic of chronic obstructive pulmonary disease in exhaled breath
L Bregy, Y Nussbaumer-Ochsner, PML Sinues… - Clinical Mass …, 2018 - Elsevier
Background New mass spectrometry (MS) techniques analysing exhaled breath have the
potential to better define airway diseases. Here, we present our work to profile the volatile …
potential to better define airway diseases. Here, we present our work to profile the volatile …
[HTML][HTML] A proposed roadmap for Parkinson's disease proof of concept clinical trials investigating compounds targeting alpha-synuclein
KM Merchant, JM Cedarbaum… - Journal of …, 2019 - content.iospress.com
The convergence of human molecular genetics and Lewy pathology of Parkinson's disease
(PD) have led to a robust, clinical-stage pipeline of alpha-synuclein (α-syn)-targeted …
(PD) have led to a robust, clinical-stage pipeline of alpha-synuclein (α-syn)-targeted …