[HTML][HTML] Inflammation and immune dysfunction in Parkinson disease

MG Tansey, RL Wallings, MC Houser… - Nature Reviews …, 2022 - nature.com
Parkinson disease (PD) is a progressive neurodegenerative disease that affects peripheral
organs as well as the central nervous system and involves a fundamental role of …

[HTML][HTML] Smelling the disease: Diagnostic potential of breath analysis

A Sharma, R Kumar, P Varadwaj - Molecular Diagnosis & Therapy, 2023 - Springer
Breath analysis is a relatively recent field of research with much promise in scientific and
clinical studies. Breath contains endogenously produced volatile organic components …

Dermoscopy, with and without visual inspection, for diagnosing melanoma in adults

J Dinnes, JJ Deeks, N Chuchu… - Cochrane Database …, 2018 - cochranelibrary.com
Background Melanoma has one of the fastest rising incidence rates of any cancer. It
accounts for a small percentage of skin cancer cases but is responsible for the majority of …

The versatile use of exhaled volatile organic compounds in human health and disease

AW Boots, JJBN van Berkel, JW Dallinga… - Journal of breath …, 2012 - iopscience.iop.org
Exhaled breath contains thousands of volatile organic compounds (VOCs) of which the
composition varies depending on health status. Various metabolic processes within the …

Exhaled volatile organic compounds identify patients with colorectal cancer

DF Altomare, M Di Lena, F Porcelli… - Journal of British …, 2013 - academic.oup.com
Background An effective screening tool for colorectal cancer is still lacking. Analysis of the
volatile organic compounds (VOCs) linked to cancer is a new frontier in cancer screening, as …

[HTML][HTML] Detection of cancer through exhaled breath: a systematic review

A Krilaviciute, JA Heiss, M Leja, J Kupcinskas… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Background Timely diagnosis of cancer represents a challenging task; in particular, there is
a need for reliable non-invasive screening tools that could achieve high levels of adherence …

[HTML][HTML] Investigation of VOCs associated with different characteristics of breast cancer cells

L Lavra, A Catini, A Ulivieri, R Capuano… - Scientific reports, 2015 - nature.com
The efficacy of breath volatile organic compounds (VOCs) analysis for the screening of
patients bearing breast cancer lesions has been demonstrated by using gas …

Detection of volatile organic compounds as biomarkers in breath analysis by different analytical techniques

B Buszewski, D Grzywinski, T Ligor, T Stacewicz… - Bioanalysis, 2013 - Taylor & Francis
Breath is a rich mixture containing numerous volatile organic compounds at trace amounts
(ppbv–pptv level) such as: hydrocarbons, alcohols, ketones, aldehydes, esters or …

[HTML][HTML] Real-time mass spectrometric identification of metabolites characteristic of chronic obstructive pulmonary disease in exhaled breath

L Bregy, Y Nussbaumer-Ochsner, PML Sinues… - Clinical Mass …, 2018 - Elsevier
Background New mass spectrometry (MS) techniques analysing exhaled breath have the
potential to better define airway diseases. Here, we present our work to profile the volatile …

[HTML][HTML] A proposed roadmap for Parkinson's disease proof of concept clinical trials investigating compounds targeting alpha-synuclein

KM Merchant, JM Cedarbaum… - Journal of …, 2019 - content.iospress.com
The convergence of human molecular genetics and Lewy pathology of Parkinson's disease
(PD) have led to a robust, clinical-stage pipeline of alpha-synuclein (α-syn)-targeted …