Is oxytocin “nature's medicine”?

CS Carter, WM Kenkel, EL MacLean, SR Wilson… - Pharmacological …, 2020 - ASPET
Oxytocin is a pleiotropic, peptide hormone with broad implications for general health,
adaptation, development, reproduction, and social behavior. Endogenous oxytocin and …

The oxytocin receptor: from intracellular signaling to behavior

B Jurek, ID Neumann - Physiological reviews, 2018 - journals.physiology.org
The many facets of the oxytocin (OXT) system of the brain and periphery elicited nearly
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …

Advances in the field of intranasal oxytocin research: lessons learned and future directions for clinical research

DS Quintana, A Lischke, S Grace, D Scheele… - Molecular …, 2021 - nature.com
Reports on the modulatory role of the neuropeptide oxytocin on social cognition and
behavior have steadily increased over the last two decades, stimulating considerable …

Advances in human oxytocin measurement: challenges and proposed solutions

BA Tabak, G Leng, A Szeto, KJ Parker… - Molecular …, 2023 - nature.com
Oxytocin, a neuropeptide known for its role in reproduction and socioemotional processes,
may hold promise as a therapeutic agent in treating social impairments in patient …

Gender differences in social anxiety disorder: A review

M Asher, A Asnaani, IM Aderka - Clinical psychology review, 2017 - Elsevier
Gender differences in social anxiety disorder (SAD) have not received much empirical
attention despite the large body of research on the disorder, and in contrast to significant …

The social salience hypothesis of oxytocin

SG Shamay-Tsoory, A Abu-Akel - Biological psychiatry, 2016 - Elsevier
Oxytocin is a nonapeptide that also serves as a neuromodulator in the human central
nervous system. Over the last decade, a sizeable body of literature has examined its effects …

Intranasal oxytocin: myths and delusions

G Leng, M Ludwig - Biological psychiatry, 2016 - Elsevier
Despite widespread reports that intranasal application of oxytocin has a variety of behavioral
effects, very little of the huge amounts applied intranasally appears to reach the …

Kinetics and dose dependency of intranasal oxytocin effects on amygdala reactivity

FB Spengler, J Schultz, D Scheele, M Essel, W Maier… - Biological …, 2017 - Elsevier
Background Current neuroimaging perspectives on a variety of mental disorders emphasize
dysfunction of the amygdala. The neuropeptide oxytocin (OXT), a key mediator in the …

The oxytocin receptor gene (OXTR) is associated with autism spectrum disorder: a meta-analysis

D LoParo, ID Waldman - Molecular psychiatry, 2015 - nature.com
The oxytocin receptor gene (OXTR) has been studied as a risk factor for autism spectrum
disorder (ASD) owing to converging evidence from multiple levels of analysis that oxytocin …

Assembling the puzzle: pathways of oxytocin signaling in the brain

V Grinevich, HS Knobloch-Bollmann, M Eliava… - Biological …, 2016 - Elsevier
Oxytocin (OT) is a neuropeptide, which can be seen to be one of the molecules of the
decade due to its profound prosocial effects in nonvertebrate and vertebrate species …