Numerous noncoding transcripts of unknown function have recently been identified. In this
study, we report a novel mechanism that relies on transcription of noncoding RNA prt (pho1 …

The Mpk1 MAPK of the yeast cell wall integrity pathway uses a noncatalytic mechanism to
activate transcription of stress-induced genes by recruitment of initiation factors to target …

Non-coding transcripts originating from bidirectional promoters have been reported in a
wide range of organisms. In yeast, these divergent transcripts can be subdivided into two …

In Saccharomyces cerevisiae, short noncoding RNA (ncRNA) generated by RNA
polymerase II (Pol II) are terminated by the NRD complex consisting of Nrd1, Nab3, and …

Transcriptomewide interrogation of eukaryotic genomes has unveiled the pervasive nature
of RNA polymerase II transcription. Virtually, any DNA region with an accessible chromatin …

The exosome and its nuclear specific subunit Rrp6 form a 3'-5'exonuclease complex that
regulates diverse aspects of RNA biology including 3'end processing and degradation of a …

DNA replication and RNA transcription compete for the same substrate during S phase.
Cells have evolved several mechanisms to minimize such conflicts. Here, we identify the …

Termination of RNA polymerase II (RNAPII) transcription is a fundamental step of gene
expression that is critical for determining the borders between genes. In budding yeast …

Pervasive transcription is widespread and needs to be controlled in order to avoid
interference with gene expression. In Saccharomyces cerevisiae, the highly conserved …

RNA-binding proteins play a key role in shaping gene expression profiles during stress,
however, little is known about the dynamic nature of these interactions and how this …