Ferroptosis, a unique modality of cell death with mechanistic and morphological differences
from other cell death modes, plays a pivotal role in regulating tumorigenesis and offers a …

Emerging evidence suggests that ferroptosis, a unique regulated cell death modality that is
morphologically and mechanistically different from other forms of cell death, plays a vital role …

Abstract Ischemia-reperfusion (I/R) injury paradoxically occurs during reperfusion following
ischemia, exacerbating the initial tissue damage. The limited understanding of the intricate …

Ferroptosis is an iron-driven cell death modality characterized by iron accumulation and
excessive lipid peroxidation. Ferroptosis is closely related to mitochondrial function, as …

Ischemia-reperfusion (I/R) injury is a major challenge in perioperative medicine that
contributes to pathological damage in various conditions, including ischemic stroke …

Stroke is one of the leading causes of death and long-term disability worldwide. More than
80% of strokes are ischemic, caused by an occlusion of cerebral arteries. Without question …

Stroke and acute myocardial infarction are leading causes of mortality worldwide. The latter
accounts for approximately 9 million deaths annually. In turn, ischemic stroke is a significant …

Ischemic stroke is an acute cerebrovascular disease with a high morbidity, mortality, and
disability rate. Persistent ischemia of brain tissue can cause irreversible damage to neurons …

Ferroptosis plays an important role in the early stage of myocardial ischemia/reperfusion
(MI/R) injury, which is closely associated with the antioxidant damage of mitochondrial …

Cerebral ischemia and reperfusion are related to various situations like injuries after various
traumas, oxidative stress, increased calcium ion, capillary hypoperfusion, microvascular …