BACKGROUND The placenta is the functional interface between the mother and the fetus
during pregnancy, and a critical determinant of fetal growth and life-long health. In the first …

Linoleic acid (LA) and alpha linolenic acid (ALA) belong to the n− 6 (omega-6) and n− 3
(omega-3) series of polyunsaturated fatty acids (PUFA), respectively. They are defined …

In an era marked by the increasing prevalence of obesity, diabetes, and cardiovascular
disease, the nuclear receptor peroxisome proliferator-activated receptor γ (PPARγ) has …

The authors review the current data on the presence and reported biological effects in fish of
some of the most commonly detected pharmaceuticals in the aquatic environment; namely …

Acrolein is a typical food and environmental pollutant and a risk factor for diabetes. The
primary pathogenesis of diabetes is insulin deficiency and resistance. Ferroptosis is an iron …

The question whether dietary habits and lifestyle have influence on the course of multiple
sclerosis (MS) is still a matter of debate, and at present, MS therapy is not associated with …

Successful implantation is the result of reciprocal interactions between the implantation-
competent blastocyst and receptive uterus. Although various cellular aspects and molecular …

Metabolic syndrome is estimated to affect more than one in five adults, and its prevalence is
growing in the adult and pediatric populations. The most widely recognized metabolic risk …

Oleylethanolamide (OEA) is a naturally occurring lipid that regulates satiety and body
weight,. Although structurally related to the endogenous cannabinoid anandamide, OEA …

Nuclear receptors are multi-domain transcription factors that bind to DNA elements from
which they regulate gene expression. The peroxisome proliferator-activated receptors …