Two Signaling Modes Are Better than One: Flux-Independent Signaling by Ionotropic Glutamate Receptors Is Coming of Age
V Brunetti, T Soda, R Berra-Romani, G De Sarro… - Biomedicines, 2024 - mdpi.com
Glutamate is the major excitatory neurotransmitter in the central nervous system.
Glutamatergic transmission can be mediated by ionotropic glutamate receptors (iGluRs) …
Glutamatergic transmission can be mediated by ionotropic glutamate receptors (iGluRs) …
Lysosomal TRPML1 triggers global Ca2+ signals and nitric oxide release in human cerebrovascular endothelial cells
V Brunetti, R Berra-Romani, F Conca, T Soda… - Frontiers in …, 2024 - frontiersin.org
Lysosomal Ca2+ signaling is emerging as a crucial regulator of endothelial Ca2+ dynamics.
Ca2+ release from the acidic vesicles in response to extracellular stimulation is usually …
Ca2+ release from the acidic vesicles in response to extracellular stimulation is usually …
Increased TRPV4 channel expression enhances and impairs blood vessel function in hypertension
Background: Endothelial cell TRPV4 channels provide a control point that is pivotal in
regulating blood vessel diameter by mediating the Ca2+-dependent release of endothelial …
regulating blood vessel diameter by mediating the Ca2+-dependent release of endothelial …
Ca2+] i Signal Dynamics Modeling in Injured Endothelial Cells
M Sanchez-Tecuatl - 2024 - inaoe.repositorioinstitucional.mx
The endothelium is the innermost tissue of the cardiovascular system in constant contact
with blood cells and molecules. As a semipermeable barrier, it plays a critical role in the …
with blood cells and molecules. As a semipermeable barrier, it plays a critical role in the …