The major innate immune cell types involved in tuberculosis (TB) infection are
macrophages, dendritic cells (DCs), neutrophils and natural killer (NK) cells. These immune …

Diabetes has been recognized as an important risk factor for a variety of intracellular
bacterial infections, but research into the dysregulated immune mechanisms contributing to …

The defining pathology of tuberculosis is the granuloma, an organized structure derived from
host immune cells that surrounds infecting Mycobacterium tuberculosis. As the location of …

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) and Coronavirus disease-
2019 (COVID-19), whose etiologic agent is severe acute respiratory syndrome coronavirus …

A major challenge in tuberculosis (TB) is to improve current vaccination and therapeutic
strategies and this requires a fine understanding of the mechanisms that mediate protection …

Human NK cells display extensive phenotypic and functional heterogeneity among healthy
individuals, but the mechanism responsible for this variation is still largely unknown. Here …

Tuberculosis remains a major health threat in much of the world. New vaccines against
Mycobacterium tuberculosis are essential for preventing infection, disease, and …

Tuberculosis (TB), caused by Mycobacterium tuberculosis (M. tb), continues to be one of the
most prevalent infectious diseases in the world. There is an upward trend in occurrence due …

The synergy between Mycobacterium tuberculosis (Mtb) and HIV in coinfected patients has
profoundly impacted global mortality because of tuberculosis (TB) and AIDS. HIV …

Despite co-evolving with humans for centuries and being intensely studied for decades, the
immune correlates of protection against Mycobacterium tuberculosis (Mtb) have yet to be …