Innate immunity in tuberculosis: host defense vs pathogen evasion
CH Liu, H Liu, B Ge - Cellular & molecular immunology, 2017 - nature.com
The major innate immune cell types involved in tuberculosis (TB) infection are
macrophages, dendritic cells (DCs), neutrophils and natural killer (NK) cells. These immune …
macrophages, dendritic cells (DCs), neutrophils and natural killer (NK) cells. These immune …
Immunological mechanisms contributing to the double burden of diabetes and intracellular bacterial infections
Diabetes has been recognized as an important risk factor for a variety of intracellular
bacterial infections, but research into the dysregulated immune mechanisms contributing to …
bacterial infections, but research into the dysregulated immune mechanisms contributing to …
In the thick of it: formation of the tuberculous granuloma and its effects on host and therapeutic responses
MR Cronan - Frontiers in immunology, 2022 - frontiersin.org
The defining pathology of tuberculosis is the granuloma, an organized structure derived from
host immune cells that surrounds infecting Mycobacterium tuberculosis. As the location of …
host immune cells that surrounds infecting Mycobacterium tuberculosis. As the location of …
Initial immune response after exposure to Mycobacterium tuberculosis or to SARS-COV-2: similarities and differences
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) and Coronavirus disease-
2019 (COVID-19), whose etiologic agent is severe acute respiratory syndrome coronavirus …
2019 (COVID-19), whose etiologic agent is severe acute respiratory syndrome coronavirus …
Pro-and anti-inflammatory cytokines in tuberculosis: a two-edged sword in TB pathogenesis
MP Etna, E Giacomini, M Severa, EM Coccia - Seminars in immunology, 2014 - Elsevier
A major challenge in tuberculosis (TB) is to improve current vaccination and therapeutic
strategies and this requires a fine understanding of the mechanisms that mediate protection …
strategies and this requires a fine understanding of the mechanisms that mediate protection …
TIGIT expression levels on human NK cells correlate with functional heterogeneity among healthy individuals
F Wang, H Hou, S Wu, Q Tang, W Liu… - European journal of …, 2015 - Wiley Online Library
Human NK cells display extensive phenotypic and functional heterogeneity among healthy
individuals, but the mechanism responsible for this variation is still largely unknown. Here …
individuals, but the mechanism responsible for this variation is still largely unknown. Here …
The importance of first impressions: early events in Mycobacterium tuberculosis infection influence outcome
AM Cadena, JAL Flynn, SM Fortune - MBio, 2016 - Am Soc Microbiol
Tuberculosis remains a major health threat in much of the world. New vaccines against
Mycobacterium tuberculosis are essential for preventing infection, disease, and …
Mycobacterium tuberculosis are essential for preventing infection, disease, and …
Mechanisms of Control of Mycobacterium tuberculosis by NK Cells: Role of Glutathione
M Allen, C Bailey, I Cahatol, L Dodge, J Yim… - Frontiers in …, 2015 - frontiersin.org
Tuberculosis (TB), caused by Mycobacterium tuberculosis (M. tb), continues to be one of the
most prevalent infectious diseases in the world. There is an upward trend in occurrence due …
most prevalent infectious diseases in the world. There is an upward trend in occurrence due …
CD4+ T-cell–independent mechanisms suppress reactivation of latent tuberculosis in a macaque model of HIV coinfection
TW Foreman, S Mehra, DN LoBato… - Proceedings of the …, 2016 - National Acad Sciences
The synergy between Mycobacterium tuberculosis (Mtb) and HIV in coinfected patients has
profoundly impacted global mortality because of tuberculosis (TB) and AIDS. HIV …
profoundly impacted global mortality because of tuberculosis (TB) and AIDS. HIV …
It Takes a Village: The Multifaceted Immune Response to Mycobacterium tuberculosis Infection and Vaccine-Induced Immunity
SE Larsen, BD Williams, M Rais, RN Coler… - Frontiers in …, 2022 - frontiersin.org
Despite co-evolving with humans for centuries and being intensely studied for decades, the
immune correlates of protection against Mycobacterium tuberculosis (Mtb) have yet to be …
immune correlates of protection against Mycobacterium tuberculosis (Mtb) have yet to be …