Background: Current guidelines recommend the use of a combination of inhaled β2 agonists
and anticholinergics, particularly for patients with acute severe or life threatening asthma in …

Objectives: To provide physicians with current guidelines for the diagnosis and optimal
management of asthma in children and adults, including pregnant women and the elderly, in …

Acute severe asthma remains a major economic and health burden. The natural history of
acute decompensations is one of resolution and only about 0.4% of patients succumb …

Background Anticholinergic medications such as ipratropium improve the pulmonary
function of patients with acute exacerbations of asthma, but their effect on hospitalization …

Purpose: To review the literature to determine whether inhaled ipratropium bromide
provides additive benefits to adults with acute asthma who are being treated with beta …

We designed a larger, double-blind, randomized, prospective trial to test our hypothesis that
patients with acute asthma given combination high dose therapy with ipratropium bromide …

ContextRelapses of acute asthma following emergency department (ED) discharge can be
reduced with systemic corticosteroid treatment. However, whether inhaled corticosteroids …

Study objective: This study was conducted to determine whether the addition of inhaled
ipratropium to inhaled β-agonist therapy is effective in the treatment of adults with acute …

Background Inhaled short‐acting anticholinergics (SAAC) and short‐acting beta₂‐agonists
(SABA) are effective therapies for adult patients with acute asthma who present to the …

The role for anticholinergic medications in acute asthma is not well-defined. Thus, the use of
therapy with anticholinergics and β 2-agonists, either simultaneously or in sequence, has …