The ability to gain spatiotemporal information, and in some cases achieve spatiotemporal
control, in the context of drug delivery makes theranostic fluorescent probes an attractive …

Hydrogenase is a paradigm of highly efficient biocatalyst for H 2 production and utilization
evolved in nature. A dilemma is that despite the high activity and efficiency expected for …

Life on Earth evolved in the presence of hydrogen peroxide, and other peroxides also
emerged before and with the rise of aerobic metabolism. They were considered only as toxic …

Selenium (Se) is of fundamental importance to human health as an essential trace element,
mainly through regulation of selenoproteins (SePs). Therefore, monitoring Se transformation …

Selenium as a biologically active element lends much support to health maintenance and
disease prevention. It is now presenting pleiotropic effects on therapy and drug delivery. In …

Organoselenium ligands have attracted great attention among researchers during the past
two decades. Various homogeneous, heterogeneous and nanocatalytic systems have been …

Living organisms use selenium mainly in the form of selenocysteine in the active site of
oxidoreductases. Here, selenium's unique chemistry is believed to modulate the reaction …

The ability to construct a peptide or protein in a spatio-specific manner is of great interest for
therapeutic and biochemical research. However, the various functional groups present in …

A diselenide/disulfide unit was introduced into camptothecin (CPT), and two selenoprodrugs
(eg, CPT–Se3 and CPT–Se4) were identified to show improved potency in killing cancer …

Specialized cellular networks of oxidoreductases coordinate the dithiol/disulfide-exchange
reactions that control metabolism, protein regulation, and redox homeostasis. For probes to …