Recent insights into the roles of circular RNAs in human brain development and neurologic diseases
S Najafi, SMA Zarch, J Majidpoor, S Pordel… - International Journal of …, 2023 - Elsevier
Circular RNAs (circRNAs) are a novel class of non-coding RNAs. They are single-stranded
RNA transcripts characterized with a closed loop structure making them resistant to …
RNA transcripts characterized with a closed loop structure making them resistant to …
microRNAs in Parkinson's disease: from pathogenesis to novel diagnostic and therapeutic approaches
L Leggio, S Vivarelli, F L'Episcopo, C Tirolo… - International journal of …, 2017 - mdpi.com
Parkinson's disease (PD) is the most prevalent central nervous system (CNS) movement
disorder and the second most common neurodegenerative disease overall. PD is …
disorder and the second most common neurodegenerative disease overall. PD is …
A Parkinson's disease Circ RNA s resource reveals a link between circ SLC 8A1 and oxidative stress
M Hanan, A Simchovitz, N Yayon… - EMBO molecular …, 2020 - embopress.org
Circular RNA s (circ RNA s) are brain‐abundant RNA s of mostly unknown functions. To
seek their roles in Parkinson's disease (PD), we generated an RNA sequencing resource of …
seek their roles in Parkinson's disease (PD), we generated an RNA sequencing resource of …
MicroRNAs in neural development: from master regulators to fine-tuners
M Rajman, G Schratt - Development, 2017 - journals.biologists.com
The proper formation and function of neuronal networks is required for cognition and
behavior. Indeed, pathophysiological states that disrupt neuronal networks can lead to …
behavior. Indeed, pathophysiological states that disrupt neuronal networks can lead to …
Profiles of extracellular miRNA in cerebrospinal fluid and serum from patients with Alzheimer's and Parkinson's diseases correlate with disease status and features of …
K Burgos, I Malenica, R Metpally, A Courtright… - PloS one, 2014 - journals.plos.org
The discovery and reliable detection of markers for neurodegenerative diseases have been
complicated by the inaccessibility of the diseased tissue-such as the inability to biopsy or …
complicated by the inaccessibility of the diseased tissue-such as the inability to biopsy or …
Neural stem cell differentiation into mature neurons: mechanisms of regulation and biotechnological applications
MS Vieira, AK Santos, R Vasconcellos… - Biotechnology …, 2018 - Elsevier
The abilities of stem cells to self-renew and form different mature cells expand the
possibilities of applications in cell-based therapies such as tissue recomposition in …
possibilities of applications in cell-based therapies such as tissue recomposition in …
MicroRNAs in neurodegenerative diseases
MicroRNAs are small noncoding RNAs that regulate gene expression at the
posttranscriptional level in a sequence-specific manner. After their discovery in 1993 …
posttranscriptional level in a sequence-specific manner. After their discovery in 1993 …
International union of basic and clinical pharmacology CXIII: Nuclear receptor superfamily—Update 2023
The NR superfamily comprises 48 transcription factors in humans that control a plethora of
gene network programs involved in a wide range of physiologic processes. This review will …
gene network programs involved in a wide range of physiologic processes. This review will …
microRNAs: important regulators of stem cells
N Li, B Long, W Han, S Yuan, K Wang - Stem cell research & therapy, 2017 - Springer
Stem cells are undifferentiated cells and have multi-lineage differentiation potential.
Generally, stem cells are classified into adult stem cells, embryonic stem cells (ESCs) and …
Generally, stem cells are classified into adult stem cells, embryonic stem cells (ESCs) and …
Circulating miRNAs as diagnostic biomarkers for Parkinson's disease
AE Roser, L Caldi Gomes, J Schünemann… - Frontiers in …, 2018 - frontiersin.org
Parkinson's disease (PD) is the second most common neurodegenerative disorder
worldwide. Its main neuropathological hallmarks are the degeneration of dopaminergic …
worldwide. Its main neuropathological hallmarks are the degeneration of dopaminergic …