[HTML][HTML] SARS-COV-2 variants: differences and potential of immune evasion

SM Hirabara, TDA Serdan, R Gorjao… - Frontiers in cellular …, 2022 - frontiersin.org
The structural spike (S) glycoprotein of severe acute respiratory syndrome coronavirus-2
(SARS-CoV-2) plays an essential role in infection and is an important target for neutralizing …

[HTML][HTML] Characterization of SARS-CoV-2 different variants and related morbidity and mortality: a systematic review

SA SeyedAlinaghi, P Mirzapour, O Dadras… - European journal of …, 2021 - Springer
Abstract Introduction Coronavirus Disease-2019 (SARS-CoV-2) started its devastating
trajectory into a global pandemic in Wuhan, China, in December 2019. Ever since, several …

[HTML][HTML] Nucleocapsid mutations R203K/G204R increase the infectivity, fitness, and virulence of SARS-CoV-2

H Wu, N Xing, K Meng, B Fu, W Xue, P Dong, W Tang… - Cell host & …, 2021 - cell.com
Previous work found that the co-occurring mutations R203K/G204R on the SARS-CoV-2
nucleocapsid (N) protein are increasing in frequency among emerging variants of concern …

[HTML][HTML] The NSP4 T492I mutation increases SARS-CoV-2 infectivity by altering non-structural protein cleavage

X Lin, Z Sha, J Trimpert, D Kunec, C Jiang, Y Xiong… - Cell Host & Microbe, 2023 - cell.com
The historically dominant SARS-CoV-2 Delta variant and the currently dominant Omicron
variants carry a T492I substitution within the non-structural protein 4 (NSP4). Based on in …

新型冠状病毒的变异株进展: 起源, 变异动力与防控措施

沈佳莹, 林剑生, 曹广文 - 上海预防医学, 2022 - sjpm.org.cn
新型冠状病毒肺炎(COVID⁃ 19) 自2019 年12 月出现后, 迅速在全球流行, 演变为全球重大公共
卫生问题. 新型冠状病毒(SARS⁃ CoV⁃ 2) 为单股正链核糖核酸(RNA) 病毒, 自然突变率较高; …

Label-free immunoassay for sensitive and rapid detection of the SARS-CoV-2 antigen based on functionalized magnetic nanobeads with chemiluminescence and …

S Wang, J Shu, A Lyu, X Huang, W Zeng… - Analytical …, 2021 - ACS Publications
Direct detection of SARS-CoV-2 in biological specimens is often challenging due to the low
abundance of viral components and lack of enough sensitivity. Herein, we developed a new …

[HTML][HTML] Next-generation bioinformatics approaches and resources for coronavirus vaccine discovery and development—A perspective review

R Chatterjee, M Ghosh, S Sahoo, S Padhi, N Misra… - Vaccines, 2021 - mdpi.com
COVID-19 is a contagious disease caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2). To fight this pandemic, which has caused a massive death toll …

[HTML][HTML] COVID-19 vaccines: computational tools and development

VC Osamor, E Ikeakanam, JU Bishung… - Informatics in Medicine …, 2023 - Elsevier
The 2019 coronavirus outbreak, also known as COVID-19, poses a serious threat to global
health and has already had widespread, devastating effects around the world. Scientists …

[HTML][HTML] Mutations of SARS-CoV-2 structural proteins in the alpha, beta, gamma, and delta variants: bioinformatics analysis

SR Khetran, R Mustafa - JMIR Bioinformatics and Biotechnology, 2023 - bioinform.jmir.org
Background: COVID-19 and Middle East Respiratory Syndrome are two pandemic
respiratory diseases caused by coronavirus species. The novel disease COVID-19 caused …

[HTML][HTML] Mutations and phylogenetic analyses of SARS-CoV-2 among imported COVID-19 from abroad in Nanjing, China

N Zhao, N Zhou, H Fan, J Ding, X Xu, X Dong… - Frontiers in …, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has become a pandemic and is threatening human health …