Umbilical cord blood transplantation: the first 25 years and beyond

KK Ballen, E Gluckman… - Blood, The Journal of the …, 2013 - ashpublications.org
Umbilical cord blood is an alternative hematopoietic stem cell source for patients with
hematologic diseases who can be cured by allogeneic hematopoietic cell transplantation …

Cord blood research, banking, and transplantation: achievements, challenges, and perspectives

H Mayani, JE Wagner, HE Broxmeyer - Bone marrow transplantation, 2020 - nature.com
The first hematopoietic transplant in which umbilical cord blood (UCB) was used as the
source of hematopoietic cells was performed in October 1988. Since then, significant …

[HTML][HTML] HIV-1 remission and possible cure in a woman after haplo-cord blood transplant

J Hsu, K Van Besien, MJ Glesby, S Pahwa, A Coletti… - Cell, 2023 - cell.com
Previously, two men were cured of HIV-1 through CCR5Δ32 homozygous (CCR5Δ32/Δ32)
allogeneic adult stem cell transplant. We report the first remission and possible HIV-1 cure in …

Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation

C Cutler, P Multani, D Robbins, HT Kim… - Blood, The Journal …, 2013 - ashpublications.org
Umbilical cord blood (UCB) is a valuable source of hematopoietic stem cells (HSCs) for use
in allogeneic transplantation. Key advantages of UCB are rapid availability and less …

[HTML][HTML] Geriatric assessment to predict survival in older allogeneic hematopoietic cell transplantation recipients

LS Muffly, M Kocherginsky, W Stock, Q Chu… - …, 2014 - ncbi.nlm.nih.gov
Allogeneic hematopoietic cell transplantation is increasingly utilized in older adults. This
study prospectively evaluated the prognostic utility of geriatric assessment domains prior to …

[HTML][HTML] Optimal practices in unrelated donor cord blood transplantation for hematologic malignancies

JN Barker, J Kurtzberg, K Ballen, M Boo… - Biology of Blood and …, 2017 - Elsevier
Unrelated donor cord blood transplantation (CBT) results in disease-free survival
comparable to that of unrelated adult donor transplantation in patients with hematologic …

[HTML][HTML] Improving engraftment and immune reconstitution in umbilical cord blood transplantation

R Danby, V Rocha - Frontiers in immunology, 2014 - frontiersin.org
Umbilical cord blood (UCB) is an important source of hematopoietic stem cells (HSC) for
allogeneic transplantation when HLA-matched sibling and unrelated donors (MUD) are …

Selection of optimal alternative graft source: mismatched unrelated donor, umbilical cord blood, or haploidentical transplant

KK Ballen, J Koreth, YB Chen, BR Dey… - Blood, The Journal of …, 2012 - ashpublications.org
Only 30% of patients who require an allogeneic hematopoietic cell transplant will have an
HLA-matched sibling donor. A search for an unrelated donor will be undertaken for patients …

Results from a multidisciplinary clinic guided by geriatric assessment before stem cell transplantation in older adults

BA Derman, K Kordas, J Ridgeway, S Chow… - Blood …, 2019 - ashpublications.org
Limitations found on geriatric assessment (GA) track with worse outcomes after
hematopoietic cell transplantation (HCT). We report on a multidisciplinary team clinic (MDC) …

Emerging concepts in haematopoietic cell transplantation

HW Li, M Sykes - Nature Reviews Immunology, 2012 - nature.com
Haematopoietic cell transplantation (HCT) is the most widely used form of cellular therapy. It
is the only known cure for some haematological malignancies and has recently been used …