Patient-derived xenograft (PDX) models, in which tumor tissues from patients are implanted
into immunocompromised or humanized mice, have shown superiority in recapitulating the …

Simple Summary It was found that long-established tumor-derived cell lines do not
adequately reproduce drug sensitivity and behavior of a real human cancers. Therefore …

Simple Summary The chorioallantoic membrane (CAM) model is an alternative in vivo test
system for the study of hallmarks of cancer such as angiogenesis, tumor growth, immune …

Despite the advancements made in the diagnosis and treatment of cancer, the stages
associated with metastasis remain largely incurable and represent the primary cause of …

Considering cancer not only as malignant cells on their own but as a complex disease in
which tumor cells interact and communicate with their microenvironment has motivated the …

Breast cancer (BRCA) is one of the most common cancers in women. Copper (Cu) is an
essential trace element implicated in many physiological processes and human diseases …

To maintain their growth rate, cancer cells must secure a supply of fatty acids, which are
necessary for building cell membranes and maintaining energy processes. This is one of the …

Background: Adjuvant radiotherapy (RT) is an integral component of a multidisciplinary
treatment strategy for early-stage breast cancer. It significantly reduces the incidence of loco …

The chorioallantoic membrane (CAM) can be used as a valuable research tool to examine
tumors. The CAM can be used to investigate processes such as migration, invasion, and …

Simple Summary The chorioallantoic membrane (CAM) is a highly vascularized membrane
found in avian eggs. Tumor cell lines can be grown on the CAM, which allows for the further …