Cryptococcus spp. are environmental fungi that first must adapt to the host environment
before they can cause life-threatening meningitis in immunocompromised patients. Host …

Carbon dioxide supplies carbon for photosynthetic species and is a major product of
respiration for all life forms. Inside the human body where CO 2 is a by-product of the …

The sophisticated ability of living organisms to sense and respond to external stimuli is
critical for survival. This is particularly true for fungal pathogens, where the capacity to adapt …

Systemic cryptococcosis is fatal without treatment. Even with the current antifungal therapies,
this disease kills 180,000 of 225,000 infected people annually. Exposure to the causative …

Cryptococcus neoformans causes cryptococcal meningoencephalitis, a disease that kills
more than 180,000 people annually. Contributing to its success as a fungal pathogen is its …

Cryptococcus neoformans is a fungal pathogen of the top critical priority recognized by the
World Health Organization. This clinically important fungus also serves as a eukaryotic …

Systemic cryptococcosis is often fatal even with the current antifungal therapy and there is
no vaccine available. Induction therapy with amphotericin B (AmB) is essential for its …

Cryptococcus spp. are environmental fungi that first must adapt to the host environment
before they can cause life-threatening meningitis in immunocompromised patients. Host CO …

Group III hybrid histidine kinases (HHK3) are known molecular targets of the widely used
fungicidal agent fludioxonil which indirectly converts these kinases to a phosphatase form …