Heart Journal. In the inaugural issue of that journal, in October 1925, Dr Conner wrote that
the “newly awakened interest in disorders of the cardiovascular system” has rapidly led to …

Myocardial infarction often occurs among persons without traditional risk factors, and it has
been hypothesized that assessment of “novel” markers may help identify persons who are …

Endogenous tissue-type plasminogen activator (tPA) has been hypothesised to be a marker
of baseline fibrinolytic capacity. We therefore tested whether tPA antigen is associated with …

BACKGROUND Plasma levels of D-dimer, the primary degradation product of cross-linked
fibrin, are elevated in several acute thrombotic disorders. However, whether elevated D …

The Progetto Lombardo Atero-Trombosi (PLAT) Study was a prospective, multicenter,
multidisciplinary study of the association among hemostatic variables, conventional risk …

▪ Objective: To investigate whether abnormalities in blood viscosity predict a poor prognosis
for subsequent cardiovascular events in stroke survivors.▪ Design: Nested case-control study …

The exact role of the fibrinolytic system in the pathogenesis of stroke remains to be
established. Elevated circulating levels of plasminogen activator inhibitor-1, the principle …

OBJECTIVE--To examine the associations between air temperature and risk factors for
ischaemic heart disease. METHOD--Data on risk factors are available from up to 2036 men …

Oxidant stress leads to covalent oxidative modification of several plasma proteins, chief
among which is fibrinogen. Aspirin can nonenzymatically acetylate fibrinogen's lysine …

We evaluated 106 subjects with and 109 subjects without a history of ischemic stroke. All
were attending a metabolic ward. The two groups were compared for major risk factors for …