Huntington's disease (HD) is an adult-onset neurodegenerative disease caused by a
trinucleotide CAG repeat expansion in the HTT gene. While the pathogenesis of HD is …

Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder caused by
pathogenic expansions of the triplet cytosine-adenosine-guanosine (CAG) within the …

Abstract Models of Huntington disease (HD) recapitulate some neuropathological features of
the disease. However, a global natural history of neuroanatomy in a mouse expressing full …

Huntington's disease (HD) is a genetic neurodegenerative disorder characterized by
neuronal loss and motor dysfunction. Although there is no effective treatment, stem cell …

Inflammation is a growing area of research in neurodegeneration. In Huntington's disease
(HD), a fatal inherited neurodegenerative disease caused by a CAG-repeat expansion in the …

We used behavioral testing and morphological methods to detail the progression of basal
ganglia neuron type‐specific pathology and the deficits stemming from them in male …

Huntington's disease (HD) is an autosomal-dominant inherited neurological disorder caused
by a genetic mutation in the IT15 gene. This neurodegenerative disorder is caused by a …

There is morphological evidence for differential alterations in striatal medium-sized spiny
neurons (MSNs) giving rise to the direct and indirect output pathways in Huntington's …

Background: Huntington's disease (HD) is a neurological disorder caused by mutations in
the huntingtin (HTT) gene, the product of which leads to selective and progressive neuronal …

Abstract Calcium (Ca 2+) plays a central role in regulating many cellular processes and
influences cell survival. Several mechanisms can disrupt Ca 2+ homeostasis to trigger cell …