Direct oral anticoagulants in the treatment of venous thromboembolism: Use in patients with advanced renal impairment, obesity, or other weight-related special …

PP Dobesh, MM Kernan… - Seminars in Respiratory …, 2021 - thieme-connect.com
There are currently more than 7 million patients taking a direct oral anticoagulant (DOAC),
with more new prescriptions per year than warfarin. Despite impressive efficacy and safety …

Direct Oral Anticoagulants for the Treatment of Venous Thromboembolism in Obesity

Q Hattaway, JA Starr, NA Pinner - Journal of Pharmacy …, 2023 - journals.sagepub.com
Background: Direct oral anticoagulants (DOACs) are known to have similar efficacy with a
decreased risk of bleeding when compared to warfarin for the treatment of venous …

Management of venous thromboembolism in morbidly obese patients: a 10-year review

B Wee, B Lui, J Lai, Z Khattak, A Kwok… - Journal of Thrombosis …, 2023 - Springer
Obesity is a known risk factor for venous thromboembolism (VTE) and poses a unique set of
challenges in anticoagulation management. We report a 10-year experience of VTE …

Factor Xa inhibitors versus vitamin K antagonist in morbidly obese patients with venous thromboembolism: a systematic review and meta-analysis

DY Park, S An, AW Arif, MK Sana, A Vij - BMC Cardiovascular Disorders, 2023 - Springer
Introduction Guidelines have endorsed non-vitamin K antagonist oral anticoagulants
(NOACs), consisting of factor Xa inhibitors (xabans) and direct thrombin inhibitors, as the first …

Direct oral anticoagulants in patients with nonvalvular atrial fibrillation and extreme body weight.

MIM Danjuma, MN Elshafei… - … Journal of Clinical …, 2022 - search.ebscohost.com
Bodega et al.'s recent report on the efficacy and safety of direct oral anticoagulants (DOACs)
in patients with nonvalvular atrial fibrillation and extreme body weight reinforces recent …

Use of direct oral anticoagulants for acute pulmonary embolisms in obesity: a propensity-matched, multicentre case–control study

CB Samaranayake, G Keir, SAA Slader… - ERJ Open …, 2021 - Eur Respiratory Soc
Direct oral anticoagulants (DOACs) are widely used as first-line treatment for pulmonary
embolism (PE) in patients without contraindications [1]; however, limited data exists on the …

[HTML][HTML] Successful use of rivaroxaban achieving therapeutic anti-factor xa levels in a morbidly obese patient with acute intermediate-high risk pulmonary embolism

K Dah, M Porres-Aguilar, AD Rosa… - Jornal Vascular …, 2023 - SciELO Brasil
Direct oral anticoagulants (DOACs) have become the standard of care for acute and long-
term therapy for venous thromboembolism (VTE) due to their efficacy and safety profiles. The …

[PDF][PDF] Comparing the Efficacy and Safety of Apixaban Versus Warfarin in Morbidly Obese Patients

SN Alotaibi, H Hasan, H Metwali, M Aseeri - Cureus, 2022 - cureus.com
This study was conducted to evaluate the efficacy and safety of apixaban versus warfarin in
morbidly obese patients. A total of 250 morbidly obese patients with a body mass index …

Pharmacist Practice Patterns Regarding Direct Oral Anticoagulants for Treatment of Venous Thromboembolism

DM Kaylor, AJ Johnson, SL Berardi… - Hospital …, 2023 - journals.sagepub.com
Background: Direct oral anticoagulants (DOACs) are increasingly prescribed for the
treatment of venous thromboembolism (VTE). However, little is known regarding …

The “Obesity Paradox” and the use of NOAC

R Bottino, A Carbone, B Liccardo, P Golino… - … : From Pharmacology to …, 2021 - Springer
Obesity is a worldwide health problem at increasing incidence associated with high
morbidity and mortality. Although obesity increases patients' cardiovascular (CV) risk, more …