Membraneless cytoplasmic condensates of mRNAs and proteins, known as RNA granules,
play pivotal roles in the regulation of mRNA fate. Their maintenance fine-tunes time and …

Alternative splicing (AS) is a fundamental process that governs almost all aspects of cellular
functions, and dysregulation in this process has been implicated in tumor initiation …

The mammalian neocortex underlies our perception of sensory information, performance of
motor activities, and higher-order cognition. During mammalian embryogenesis, radial glial …

Single-cell transcriptional profiling has rapidly advanced our understanding of the
embryonic hematopoiesis; however, whether and what role RNA alternative splicing (AS) …

Public archives of next-generation sequencing data are growing exponentially, but the
difficulty of marshaling this data has led to its underutilization by scientists. Here, we present …

Alternative splicing of neuronal genes is controlled partly by the coordinated action of
polypyrimidine tract binding proteins (PTBPs). While PTBP1 is ubiquitously expressed …

Alternative RNA splicing is a key step in gene expression that allows generation of
numerous messenger RNA transcripts encoding proteins of varied functions from the same …

Recent advances in long-read sequencing solve inaccuracies in alternative transcript
identification of full-length transcripts in short-read RNA-Seq data, which encourages the …

Aging is a physiological and progressive phenomenon in all organisms' life cycle,
characterized by the accumulation of degenerative processes triggered by several …

Postsynaptic proteins play crucial roles in synaptic function and plasticity. During brain
development, alterations in synaptic number, shape, and stability occur, known as synapse …