Mesenchymal stem cell migration and tissue repair
Mesenchymal stem cells (MSCs) are multilineage cells with the ability to self-renew and
differentiate into a variety of cell types, which play key roles in tissue healing and …
differentiate into a variety of cell types, which play key roles in tissue healing and …
3D cell culture models as recapitulators of the tumor microenvironment for the screening of anti-cancer drugs
Simple Summary Three-dimensional (3D) cell culture models have been proposed as
alternatives for initial drug screening to increase drug development efficiency. In addition to …
alternatives for initial drug screening to increase drug development efficiency. In addition to …
The horizon of materiobiology: a perspective on material-guided cell behaviors and tissue engineering
Although the biological functions of cell and tissue can be regulated by biochemical factors
(eg, growth factors, hormones), the biophysical effects of materials on the regulation of …
(eg, growth factors, hormones), the biophysical effects of materials on the regulation of …
Could 3D models of cancer enhance drug screening?
Cancer is a multifaceted pathology, where cellular and acellular players interact to drive
cancer progression and, in the worst-case, metastasis. The current methods to investigate …
cancer progression and, in the worst-case, metastasis. The current methods to investigate …
A hydrogel bioink toolkit for mimicking native tissue biochemical and mechanical properties in bioprinted tissue constructs
Advancement of bioprinting technology is limited by the availability of materials that both
facilitate bioprinting logistics as well as support cell viability and function by providing tissue …
facilitate bioprinting logistics as well as support cell viability and function by providing tissue …
In vitro matured human pluripotent stem cell–derived cardiomyocytes form grafts with enhanced structure and function in injured hearts
W Dhahri, T Sadikov Valdman, D Wilkinson, E Pereira… - Circulation, 2022 - Am Heart Assoc
Background: Human pluripotent stem cell (hPSC)–derived cardiomyocytes (hPSC-CMs)
have tremendous promise for application in cardiac regeneration, but their translational …
have tremendous promise for application in cardiac regeneration, but their translational …
3D cancer models: the need for a complex stroma, compartmentalization and stiffness
J Pape, M Emberton, U Cheema - Frontiers in Bioengineering and …, 2021 - frontiersin.org
The use of tissue-engineered 3D models of cancer has grown in popularity with recent
advances in the field of cancer research. 3D models are inherently more biomimetic …
advances in the field of cancer research. 3D models are inherently more biomimetic …
Keloid disorder: fibroblast differentiation and gene expression profile in fibrotic skin diseases
EJ Macarak, PJ Wermuth… - Experimental …, 2021 - Wiley Online Library
Keloid disorder, a group of fibroproliferative skin diseases, is characterized by unremitting
accumulation of the extracellular matrix (ECM) of connective tissue, primarily collagen, to …
accumulation of the extracellular matrix (ECM) of connective tissue, primarily collagen, to …
[HTML][HTML] Physico-chemical modification of gelatine for the improvement of 3D printability of oxidized alginate-gelatine hydrogels towards cartilage tissue engineering
This work explored 3D bioplotting to mimic the intrinsic hierarchical structure of natural
articular cartilage. Alginate dialdehyde-gelatine (ADA-GEL) was used as a hydrogel ink to …
articular cartilage. Alginate dialdehyde-gelatine (ADA-GEL) was used as a hydrogel ink to …
Mature human white adipocytes cultured under membranes maintain identity, function, and can transdifferentiate into brown-like adipocytes
White adipose tissue (WAT) is a central factor in the development of type 2 diabetes, but
there is a paucity of translational models to study mature adipocytes. We describe a method …
there is a paucity of translational models to study mature adipocytes. We describe a method …