Human T-cell leukemia virus type 1 (HTLV-1) is the causative agent of a fatal malignancy
known as adult T-cell leukemia (ATL). One way to address the pathology of the disease lies …

Human T cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia-lymphoma (ATL)
and inflammatory diseases. The HTLV-1 bZIP factor (HBZ) gene is constantly expressed in …

Human T cell leukemia virus type 1 (HTLV-1) is an oncogenic retrovirus responsible for the
development of adult T-cell leukemia (ATL). Although HTLV-1 harbors an oncogene, tax …

Highlights•HTLV-1 primarily transmits by cell-to-cell contact.•HTLV-1 increases the number
of infected cells by clonal proliferation to facilitate its transmission.•HTLV-1 bZIP factor (HBZ) …

Human T-cell leukaemia virus type 1 (HTLV-1) causes not only adult T-cell leukaemia-
lymphoma (ATL), but also inflammatory diseases including HTLV-1-associated …

Human T-cell leukemia virus type 1 (HTLV-1) is the only identified oncogenic human
retrovirus. HTLV-1 infects approximately 5–10 million people worldwide and is the infectious …

Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic cause of adult T-cell
leukemia/lymphoma (ATL) and encodes a viral oncoprotein (Hbz) that is consistently …

Most proteins expressed by endogenous and exogenous retroviruses are encoded in the
sense (positive) strand of the genome and are under the control of regulatory elements …

HTLV-1 plus-strand transcription begins with the production of doubly-spliced tax/rex
transcripts, the levels of which are usually undetectable in freshly isolated peripheral blood …

The complex retrovirus, human T-cell leukemia virus type 1 (HTLV-1), primarily infects CD4+
T-cells in vivo. Infectious spread within this cell population requires direct contact between …