A2A adenosine receptor signaling in lymphocytes and the central nervous system regulates inflammation during experimental autoimmune encephalomyelitis
JH Mills, DG Kim, A Krenz, JF Chen… - The Journal of …, 2012 - journals.aai.org
Extracellular adenosine has an important role in regulating the severity of inflammation
during an immune response. Although there are four adenosine receptor (AR) subtypes, the …
during an immune response. Although there are four adenosine receptor (AR) subtypes, the …
Dietary caffeine consumption modulates fMRI measures
Caffeine is the most widely used stimulant in the world. The stimulant effects of caffeine are
mediated through its antagonistic properties on neuronal adenosine receptors. In addition …
mediated through its antagonistic properties on neuronal adenosine receptors. In addition …
Working memory deficits in transgenic rats overexpressing human adenosine A2A receptors in the brain
L Giménez-Llort, SN Schiffmann, T Shmidt… - Neurobiology of learning …, 2007 - Elsevier
Adenosine receptors in the central nervous system have been implicated in the modulation
of different behavioural patterns and cognitive functions although the specific role of A2A …
of different behavioural patterns and cognitive functions although the specific role of A2A …
The lesion of the rat substantia nigra pars compacta dopaminergic neurons as a model for Parkinson's disease memory disabilities
C Da Cunha, MEM Angelucci, NS Canteras… - Cellular and molecular …, 2002 - Springer
In this article we review the studies of memory disabilities in a rat model o Parkinson's
disease (PD). 2. Intranigral administration of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine …
disease (PD). 2. Intranigral administration of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine …
Distinct regional distribution of human equilibrative nucleoside transporter proteins 1 and 2 (hENT1 and hENT2) in the central nervous system
LL Jennings, C Hao, MA Cabrita, MF Vickers… - …, 2001 - Elsevier
Nucleoside transport processes play an important role in human cells in salvage of
nucleosides used in the biosynthesis of nucleic acids and in regulating endogenous …
nucleosides used in the biosynthesis of nucleic acids and in regulating endogenous …
Moonlighting adenosine deaminase: a target protein for drug development
A Cortés, E Gracia, E Moreno, J Mallol… - Medicinal research …, 2015 - Wiley Online Library
Interest in adenosine deaminase (ADA) in the context of medicine has mainly focused on its
enzymatic activity. This is justified by the importance of the reaction catalyzed by ADA not …
enzymatic activity. This is justified by the importance of the reaction catalyzed by ADA not …
Effects of adenosine A1 and A2A receptor activation on the evoked release of glutamate from rat cerebrocortical synaptosomes
M Marchi, L Raiteri, F Risso, A Vallarino… - British journal of …, 2002 - Wiley Online Library
The effects of adenosine A2A and A1 receptor activation on the release of glutamate were
studied in rat cerebral cortex synaptosomes exposed in superfusion to adenosine receptor …
studied in rat cerebral cortex synaptosomes exposed in superfusion to adenosine receptor …
Embryonic exposure to valproic acid affects the histaminergic system and the social behaviour of adult zebrafish (Danio rerio)
D Baronio, HAJ Puttonen, M Sundvik… - British journal of …, 2018 - Wiley Online Library
Background and Purpose Histamine modulates several behaviours and physiological
functions, and its deficiency is associated with neuropsychiatric disorders. Gestational intake …
functions, and its deficiency is associated with neuropsychiatric disorders. Gestational intake …
Retinal vascular development and oxygen-induced retinopathy: a role for adenosine
Adenosine is a ubiquitous molecule that is produced predominantly by catabolism of
adenosine triphosphate. Levels of this nucleoside increase dramatically with ischemia and …
adenosine triphosphate. Levels of this nucleoside increase dramatically with ischemia and …
Caffeine reverses the memory disruption induced by intra-nigral MPTP-injection in rats
MS Gevaerd, RN Takahashi, R Silveira… - Brain Research …, 2001 - Elsevier
The present study was carried out to test the possible effects of caffeine in improving the
memory deficits observed in 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyrindine (MPTP) …
memory deficits observed in 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyrindine (MPTP) …