Functions, dysfunctions and possible therapeutic relevance of adenosine A2A receptors in Huntington's disease

P Popoli, D Blum, A Martire, C Ledent, S Ceruti… - Progress in …, 2007 - Elsevier
The aim of this review is to summarize and critically discuss the complex role played by
adenosine A2A receptors (A2ARs) in Huntington's disease (HD). Since A2ARs are mainly …

Imaging neuroinflammation in multiple sclerosis using TSPO-PET

L Airas, E Rissanen, JO Rinne - Clinical and translational imaging, 2015 - Springer
Conventional MR imaging (MRI) techniques form the cornerstone of multiple sclerosis (MS)
diagnostics and clinical follow-up today. MRI is sensitive in demonstrating focal inflammatory …

Adenosine A2A receptor gene (ADORA2A) variants may increase autistic symptoms and anxiety in autism spectrum disorder

CM Freitag, K Agelopoulos, E Huy… - European child & …, 2010 - Springer
Autism spectrum disorders (ASDs) are heterogeneous disorders presenting with increased
rates of anxiety. The adenosine A 2A receptor gene (ADORA2A) is associated with panic …

Adenosine, inflammation and asthma–a review

M Livingston, LG Heaney, M Ennis - Inflammation Research, 2004 - Springer
Adenosine is a ubiquitous molecule present in every cell of the human body. It has a wide
range of physiological functions mediated predominantly through specific cell surface …

[PDF][PDF] State-of-the-art in membrane protein prediction

CP Chen, B Rost - Applied bioinformatics, 2002 - Citeseer
Membrane proteins are crucial for many biological functions and have become attractive
targets for pharmacological agents. About 10%–30% of all proteins contain membrane …

Static magnetic field exposure reproduces cellular effects of the Parkinson's disease drug candidate ZM241385

Z Wang, PL Che, J Du, B Ha, KJ Yarema - PLoS One, 2010 - journals.plos.org
Background This study was inspired by coalescing evidence that magnetic therapy may be a
viable treatment option for certain diseases. This premise is based on the ability of moderate …

Impact of genetic variations in ADORA2A gene on depression and symptoms: a cross-sectional population-based study

S Oliveira, AP Ardais, CR Bastos, M Gazal… - Purinergic …, 2019 - Springer
Genetic variants involved in adenosine metabolism and its receptors were associated with
increased risk for psychiatric disorders, including anxiety, depression, and schizophrenia …

Caffeine and cognition in functional magnetic resonance imaging

F Koppelstaetter, TD Poeppel… - Journal of …, 2010 - content.iospress.com
Caffeine has been consumed since ancient times due to its beneficial effects on attention,
psychomotor function, and memory. Caffeine exerts its action mainly through an antagonism …

The role of glial adenosine receptors in neural resilience and the neurobiology of mood disorders

D van Calker, K Biber - Neurochemical research, 2005 - Springer
Adenosine receptors were classified into A 1-and A 2-receptors in the laboratory of Bernd
Hamprecht more than 25 years ago. Adenosine receptors are instrumental to the …

Activation of Adenosine A2A Receptor Up-Regulates BDNF Expression in Rat Primary Cortical Neurons

SJ Jeon, SY Rhee, JH Ryu, JH Cheong, K Kwon… - Neurochemical …, 2011 - Springer
As a member of neurotrophin family, brain derived neurotrophic factor (BDNF) plays critical
roles in neuronal development, differentiation, synaptogenesis, and neural protection from …