Elements of the nucleoside system (nucleoside levels, 5'-nucleotidases (5'NTs) and other
nucleoside metabolic enzymes, nucleoside transporters and nucleoside receptors) are …

In the present study, we investigated the spatiotemporal properties of locomotor activity after
administration of CNS sedatives (pentobarbital and diazepam) and stimulants (theophylline …

Introduction 2.1. Adenosine implication in anxiety disorders: Data from non specific
antagonists 2.2. Role of adenosine in animal models of anxiety 3. Role of the different …

Adenosine receptors modulate dopaminergic function by regulating dopamine release in
presynaptic neurons and intracellular signaling in postsynaptic striatal neurons. To …

Syntheses and physicochemical properties of N-cycloalkyl-substituted imidazo-, pyrimido-
and 1, 3-diazepino [2, 1-f] purinediones are described. These derivatives were synthesized …

Parkinson's Disease (PD) is a long-term neurodegenerative brain disorder that mainly
affects the motor system. The causes are still unknown, and even though currently there is …

Previously we have described a novel series of potent and selective A2A receptor
antagonists (eg, 1) with excellent aqueous solubility. While these compounds are efficacious …

Antrodia cinnamomea (formerly named Antrodia camphorata) is a rare medicinal fungus. We
previously reported that it exhibits antioxidative, vasorelaxative, anti-inflammatory, and anti …

In the last few years, accumulating evidence has shown the existence of an important cross‐
talk between adenosine A2A receptors (A2ARs) and brain‐derived neurotrophic factor …

The brain A2A adenosine receptor (A2AAR) participates with the dopamine D2 receptor in
the control of movement and also might influence behavior. Because PET is an important …