Soft tissue tumor imaging in adults: European Society of Musculoskeletal Radiology-Guidelines 2023—overview, and primary local imaging: how and where?

IM Noebauer-Huhmann, FM Vanhoenacker… - European …, 2024 - Springer
Objectives Early, accurate diagnosis is crucial for the prognosis of patients with soft tissue
sarcomas. To this end, standardization of imaging algorithms, technical requirements, and …

Werner syndrome (WRN) gene variants and their association with altered function and age-associated diseases

M Lebel, RJ Monnat Jr - Ageing research reviews, 2018 - Elsevier
Werner syndrome (WS) is a heritable autosomal recessive human disorder characterized by
the premature onset of several age-associated pathologies including cancer. The protein …

Nonfunctional mutant Wrn protein leads to neurological deficits, neuronal stress, microglial alteration, and immune imbalance in a mouse model of Werner syndrome

CW Hui, MK St-Pierre, J Detuncq, L Aumailley… - Brain, behavior, and …, 2018 - Elsevier
Werner syndrome (WS) is a premature aging disorder caused by mutations in a RecQ-family
DNA helicase, WRN. Mice lacking part of the helicase domain of the WRN orthologue exhibit …

Diagnosis of idiopathic premature ovarian failure by color Doppler ultrasound under the intelligent segmentation algorithm

L Yu, X Qing - Computational and Mathematical Methods in …, 2022 - Wiley Online Library
The aim of this study was to explore the application value of transvaginal color Doppler
ultrasound based on the improved mean shift algorithm in the diagnosis of idiopathic …

The impact of vitamin C on different system models of Werner syndrome

L Aumailley, M Lebel - Antioxidants & Redox Signaling, 2021 - liebertpub.com
Significance: Werner syndrome (WS) is a rare autosomal recessive malady typified by a pro-
oxidant/proinflammatory status, genetic instability, and by the early onset of numerous age …

Adult progeria: a new mutation in the WRN gene

ML Rocha, AT Chicharo, G Sequeira… - BMJ Case Reports …, 2022 - casereports.bmj.com
Werner syndrome (WS), also known as adult progeria, is a rare autosomal recessive
inherited progeroid syndrome characterised by multiple features consistent with accelerated …

Werner syndrome associated with acroosteolysis

T Khalid, F Inam, MA Iqbal - Dermatology Online Journal, 2022 - escholarship.org
Werner syndrome (WS) is an autosomal recessive syndrome characterized by genomic
instability that affects multiple body systems. The characteristic features of the disease …

[PDF][PDF] American Journal of Surgery and Clinical Case Reports

JI Clark - 2023 - ajsuccr.org
Human variation is a cornerstone of biomedical science and patient care. In a first-year
anatomy course, medical students at one dissection table had difficulty finding the piriformis …

Síndrome de Werner: a propósito de un caso probable

MAA Aragón, MF Sierra, NFS Muñoz - Medicina & Laboratorio, 2017 - dialnet.unirioja.es
el síndrome de Werner es una patología poco frecuente, de herencia autosómica recesiva,
caracterizado por signos de envejecimiento prematuro y tendencia a desarrollar tumores …

What have we learned so far on the molecular pathogenesis of Werner syndrome using mutant mouse models of this human progeroid disorder?

M Lebel, FB Johnson - Drug Discovery Today: Disease Models, 2018 - Elsevier
Werner syndrome (WS) is a rare autosomal recessive disorder characterized by genomic
instability and the premature onset of several age-associated phenotypes. The protein …